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Protein Overview: Taf12L-PA

General Information:
Name(s) found: Taf12L-PA / FBpp0077111 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene TBP-associated factor 30kD subunit Ã?&#142;Ã?±-2 is referred to in FlyBase by the symbol Dmel\Taf12L (CG15632, FBgn0031623). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4700941..4701588. It has the cytological map location 25A3. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 138 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIID complex [ISS]
    Biological Process: male meiosis [NAS]
    spermatogenesis [NAS]
    transcription initiation from RNA polymerase II promoter [ISS]
    Molecular Function: transcription initiation factor activity [IEA]
    DNA binding [IEA]
    general RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSNMEPWSF ALNFDDSDKS SDNESHSSTR SSSRSSDTSI DTSSVEKEPA SVIESQSVPG  60
   61 GSYDIISKTN MLQFVQKIDA NSSLDDQGCD MMARIADAFV NDISMRIVKL AKYRKSDVSV 120
  121 LDLKFILKRE FNMEFPIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..65] MSA 1.026993 View MSA. No confident structure predictions are available.
    2 View Details [66..138] PSI-BLAST 32.045757 TAF(II)-20, (TAF(II)-15, hTAF12), histone fold domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  9.25279783093877 bayes_pls_golite062009
  • DNA binding
    		•  4.24625687315724 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.08606081850613 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  3.96621818094279 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.93473976418251 bayes_pls_golite062009
  • binding
    		•  3.79827182235984 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.28941584139552 bayes_pls_golite062009
  • transcription factor activity
    		•  2.31114764804139 bayes_pls_golite062009
  • protein binding
    		•  1.2861218811362 bayes_pls_golite062009
  • transcription activator activity
    		•  1.25487495162413 bayes_pls_golite062009
  • transcription factor binding
    		•  1.15204005455906 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.1297723528047 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.10331930589736 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.01502031330902 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.72554769377984 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0792897588268993 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle