Protein Overview: msl-2-PA, msl-2-PB

General Information:
Name(s) found:	msl-2-PA / FBpp0077260 [FlyBase] msl-2-PB / FBpp0077259 [FlyBase]
Description(s) found: Found 39 descriptions. SHOW ALL	The gene male-specific lethal 2 is referred to in FlyBase by the symbol Dmel\msl-2 (CG3241, FBgn0005616). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:3462213..3466111. It has the cytological map location 23F3. There is experimental evidence that it has the molecular function</span>: chromatin binding. There is experimental evidence that it is involved in the biological process</span>: dosage compensation. 75 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene male-specific lethal 2 is referred to in FlyBase by the symbol Dmel\msl-2 (CG3241, FBgn0005616). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:3462213..3466111. It has the cytological map location 23F3. There is experimental evidence that it has the molecular function</span>: chromatin binding. There is experimental evidence that it is involved in the biological process</span>: dosage compensation. 75 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	773 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] X chromosome [IDA][NAS][TAS] chromosome [NAS] X chromosome located dosage compensation complex, transcription activating [NAS][TAS] dosage compensation complex [IDA]
Biological Process:	dosage compensation [IMP] dosage compensation, by hyperactivation of X chromosome [NAS] dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome [TAS]
Molecular Function:	DNA binding [TAS] zinc ion binding [IEA] protein binding [IEA][TAS] chromatin binding [IDA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQTAYLKVT RIAMRSASNL SKRRVEELNS GLGELRQLLS CVVCCQLLVD PYSPKGKRCQ  60
   61 HNVCRLCLRG KKHLFPSCTQ CEGCSDFKTY EENRMMAAQL LCYKTLCVHL LHSALFGELA 120
  121 GMRPQVAREL VPRIKLPPKT TQEFIREGSN ISDTFDIFLP QPDLPFLKDM PTSLPAETPP 180
  181 TSAVTTPELP YDHHLNISDI EAEAAATAEQ GHFSPLPLLP TGSRMGMLSH AGQIVIATES 240
  241 SESGFMDQAW TDQVDLSGTV SVSKYTNSGN NFAVSYVMPT SATTKFDPQE LQIGQVVQMA 300
  301 DSTQLAVLAA VEETVETSTQ LTVLSTTVEE TVETSTQLEV LTSAEEPNEI SDQLANLQVE 360
  361 ESDEALVEET VEEAEGTSIP SEVVAEHMEE DQHLDVHTSQ SPTQTEMEEA VEEHVATKTQ 420
  421 LGHVQTELQD AESLQKDFED AKAAAEEAKE KEKDLHAISA ELQKEDSDEP TLKRKRTRTL 480
  481 KASQAAKIEP VPSEVKTKVQ SGKGALRRIR GKDKEEKVKP PKPKCRCGIS GSSNTLTTCR 540
  541 NSRCPCYKSY NSCAGCHCVC CKNPHKEDYV ESDEDDDLED FEMPKDVPEP MTQSEEPVVA 600
  601 EPRQEENSMA PPDSSAPISL VPLNNLQQSQ HPLVLVQNEK GEYQGFNIFQ GSKPLDPVTV 660
  661 GFTIRVQLQH TDGFGSLPQY AYIMPTIDPP NPPAPSLSPP PPPAPDREVI EPPAKKFRTS 720
  721 RTRRGRANFS ALDTVDELVS GGSRSNSAAG DRSSATDNAH SLFEEIMSGS DDL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Protein Overview: msl-2-PA, msl-2-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: