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The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster. Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster. The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes. The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome
Acc: GO:0016457
Aspect: Biological Process
Desc: The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster.
Synonyms:
  • dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016457 - dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle