Protein Overview: AIF-PB

General Information:
Name(s) found:	AIF-PB / FBpp0077504 [FlyBase]
Description(s) found: Found 19 descriptions. SHOW ALL	The gene Apoptosis inducing factor is referred to in FlyBase by the symbol Dmel\AIF (CG7263, FBgn0031392). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2151664..2155390. It has the cytological map location 22D1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: oxidoreductase activity; FAD binding. There is experimental evidence that it is involved in the biological process</span>: regulation of programmed cell death; mitochondrion organization. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; ventral nerve cord; Bolwig's organ; ommatidium; mesothoracic bristle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	739 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS] mitochondrial intermembrane space [ISS] mitochondrion [IDA]
Biological Process:	induction of apoptosis [ISS] DNA fragmentation involved in apoptosis [ISS] regulation of programmed cell death [IMP] cell redox homeostasis [IEA] oxidation reduction [IEA] mitochondrion organization [IMP]
Molecular Function:	FAD binding [IEA] oxidoreductase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIWGVRCLT QRFIRQAYIL ANRRLLGPVP QRSPPAYAPL RPAHSSLYQM VKKRTLEART  60
   61 KLQANKYPNH QVCVTKPSTT PPVEEYETAV EGAGVPAYAN AQFQAHSQSE PLFKVGFADV 120
  121 KSVCSAKDVL KSDSAKLSTS QPVLDSCKAT SPCEEFKRKR KETTCQPCDE DGTAPGGGDG 180
  181 GDEECECRMK DLRLKCLLGA LAALLAGGFL AWFMTRDTDD SEAKKAEAEE EERKRRLVAG 240
  241 LATSPPSSED LPKHVPYLII GGGTAAFSAF RAIKSNDATA KVLMISNEFR KPYMRPPLSK 300
  301 ELWYTPNPNE DPIKDYRFKQ WTGSERSLFF EPDEFFIDPE DLDDNANGGI AVAQGFSVKK 360
  361 VDAQKRIVTL NDGYEISYDE CLIATGCAPK NLPMLRDAPP SVLEKVMVYR TPDDFDRLRK 420
  421 LAAEKRSITI VGNGFIGSEL ACSLAHYSRE NNGGKVYQVF QENANMSKVL PNYLSRWTTA 480
  481 KMEAQGVCVI PNASIRSAVR DETNLKLELN NGMTLMSDVV VVCVGCTPNT DLAGPSRLEV 540
  541 DRSLGGFVVN AELEARRNLY VAGDASCFFD PLLGRRRVEH HDHSVVSGRL AGENMTGAKK 600
  601 PYQHQSMFWS DLGPEIGYEG IGLVDSSLPT VGVFALPSES ATRVDQLSES SDSDVPETST 660
  661 SSSQSSKSDA GASQDGVTCD PDEAGNYGKG VIFYLKNDKI VGILLWNLFN RIGLARTIIN 720
  721 QNKKYDDLNE VAKLFEIHA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AIF-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: