Protein Overview: FBpp0310352, FBp...

General Information:
Name(s) found:	FBpp0310352 [FlyBase] FBpp0310350 [FlyBase] FBpp0300577 [FlyBase] GABA-B-R3-PA / FBpp0077666 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24580689\|ref\|NP_523447.2\| metabotropic GABA-B receptor subtype 3, isoform A [Drosophila melanogaster] [NCBI NR] gi\|10727404\|gb\|AAF51465.2\| metabotropic GABA-B receptor subtype 3, isoform A [Drosophila melanogaster] [NCBI NR] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310352; name=GABA-B-R3-PG; parent=FBgn0031275,FBtr0343787; dbxref=FlyBase:FBpp0310352,FlyBase_Annotation_IDs:CG3022-PG; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310350; name=GABA-B-R3-PE; parent=FBgn0031275,FBtr0343785; dbxref=FlyBase:FBpp0310350,FlyBase_Annotation_IDs:CG3022-PE; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0300577; name=GABA-B-R3-PD; parent=FBgn0031275,FBtr0308257; dbxref=FlyBase:FBpp0300577,FlyBase_Annotation_IDs:CG3022-PD,REFSEQ:NP_001245826,GB_protein:AFH03503; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.56; species=Dmel; [FlyBase] The gene metabotropic GABA-B receptor subtype 3 is referred to in FlyBase by the symbol Dmel\GABA-B-R3 (CG3022, FBgn0031275). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:752800..762142. It has the cytological map location 21E2. Based on sequence similarity, it is predicted to have molecular function</span>: GABA-B receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: G-protein coupled receptor protein signaling pathway. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] >CG3022-PA translation from_gene[CG3022 GABA-B-R3 FBgn0031275] seq_release:3 mol_weight=143591 cds_boundaries:(2L:754,784..762,575[+]) aa_length:1305 transcript_info:[CG3022-RA seq_release:3] gene_info:[gene symbol:GABA-B-R3 FBgn0031275 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta] (Q9VPS7) CG3022 protein [DrosMelano7227.FASTAC.txt] (AE003588) CG3022 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3022-PA, isoform A [Drosophila melanogaster]gi\|24580689\|ref\|NP_523447.2\| CG3022-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=Fly [fly-100309-contam.fasta] metabotropic GABA-B receptor subtype 3 CG3022-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG3022-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Metabotropic GABA-B receptor subtype 3, isoform A OS=Drosophila melanogaster GN=GABA-B-R3 PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465,FlyMine:FBpp0077666,modMine:FBpp0077666; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0300577; name=GABA-B-R3-PD; parent=FBgn0031275,FBtr0308257; dbxref=FlyBase:FBpp0300577,FlyBase_Annotation_IDs:CG3022-PD,REFSEQ:NP_001245826,GB_protein:AFH03503; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465,FlyMine:FBpp0077666,modMine:FBpp0077666; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0300577; name=GABA-B-R3-PD; parent=FBgn0031275,FBtr0308257; dbxref=FlyBase:FBpp0300577,FlyBase_Annotation_IDs:CG3022-PD,REFSEQ:NP_001245826,GB_protein:AFH03503; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310350; name=GABA-B-R3-PE; parent=FBgn0031275,FBtr0343785; dbxref=GB_protein:AAN10484,REFSEQ:NP_722648,FlyBase:FBpp0310350,FlyBase_Annotation_IDs:CG3022-PE; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310352; name=GABA-B-R3-PG; parent=FBgn0031275,FBtr0343787; dbxref=GB_protein:AHN54069,REFSEQ:NP_001285554,FlyBase:FBpp0310352,FlyBase_Annotation_IDs:CG3022-PG; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465,FlyMine:FBpp0077666,modMine:FBpp0077666; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0300577; name=GABA-B-R3-PD; parent=FBgn0031275,FBtr0308257; dbxref=FlyBase:FBpp0300577,FlyBase_Annotation_IDs:CG3022-PD,REFSEQ:NP_001245826,GB_protein:AFH03503; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310350; name=GABA-B-R3-PE; parent=FBgn0031275,FBtr0343785; dbxref=GB_protein:AAN10484,REFSEQ:NP_722648,FlyBase:FBpp0310350,FlyBase_Annotation_IDs:CG3022-PE; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310352; name=GABA-B-R3-PG; parent=FBgn0031275,FBtr0343787; dbxref=GB_protein:AHN54069,REFSEQ:NP_001285554,FlyBase:FBpp0310352,FlyBase_Annotation_IDs:CG3022-PG; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Metabotropic GABA-B receptor subtype 3, isoform A OS=Drosophila melanogaster GN=GABA-B-R3 PE=4 SV=2 [DROME.fasta.20160308] FBpp0077666 type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465,FlyMine:FBpp0077666,modMine:FBpp0077666; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0300577 type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0300577; name=GABA-B-R3-PD; parent=FBgn0031275,FBtr0308257; dbxref=FlyBase:FBpp0300577,FlyBase_Annotation_IDs:CG3022-PD,REFSEQ:NP_001245826,GB_protein:AFH03503; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0310350 type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310350; name=GABA-B-R3-PE; parent=FBgn0031275,FBtr0343785; dbxref=GB_protein:AAN10484,REFSEQ:NP_722648,FlyBase:FBpp0310350,FlyBase_Annotation_IDs:CG3022-PE; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0310352 type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310352; name=GABA-B-R3-PG; parent=FBgn0031275,FBtr0343787; dbxref=GB_protein:AHN54069,REFSEQ:NP_001285554,FlyBase:FBpp0310352,FlyBase_Annotation_IDs:CG3022-PG; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0077666; name=GABA-B-R3-PA; parent=FBgn0031275,FBtr0078001; dbxref=FlyBase:FBpp0077666,FlyBase_Annotation_IDs:CG3022-PA,GB_protein:AAF51465.2,REFSEQ:NP_523447,GB_protein:AAF51465,UniProt/TrEMBL:Q9VPS7,FlyMine:FBpp0077666,modMine:FBpp0077666; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0300577; name=GABA-B-R3-PD; parent=FBgn0031275,FBtr0308257; dbxref=FlyBase:FBpp0300577,FlyBase_Annotation_IDs:CG3022-PD,REFSEQ:NP_001245826,GB_protein:AFH03503,UniProt/TrEMBL:Q9VPS7; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310350; name=GABA-B-R3-PE; parent=FBgn0031275,FBtr0343785; dbxref=GB_protein:AAN10484,REFSEQ:NP_722648,FlyBase:FBpp0310350,FlyBase_Annotation_IDs:CG3022-PE,UniProt/TrEMBL:Q9VPS7; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(753119..753730,754487..754630,755021..755296,755829..756080,756668..757030,757128..757429,757800..757938,758847..759122,759231..759549,759679..760913); ID=FBpp0310352; name=GABA-B-R3-PG; parent=FBgn0031275,FBtr0343787; dbxref=GB_protein:AHN54069,REFSEQ:NP_001285554,FlyBase:FBpp0310352,FlyBase_Annotation_IDs:CG3022-PG,UniProt/TrEMBL:Q9VPS7; MD5=1c35080e9f4480c632c7c969ec6e314a; length=1305; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1305 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA][ISS]
Biological Process:	G-protein coupled receptor protein signaling pathway [IEA][ISS]
Molecular Function:	G-protein coupled receptor activity [IEA] GABA-B receptor activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIIQPVQGT RYGPWPAVGL RLVLALAWAT SAAAAMESSA ELQALGYEAI RPGAASISTS  60
   61 SPSSSPPGES ASTVTAGGTP IPPRSDWKYK RTKVKRRQQR LNSHSNLPGS TNASHAHHLL 120
  121 NLPPRQRYLK VNQVFESERR MSPAEMQRNH GKIVLLGLFE LSTSRGPRPD GLSELGAATM 180
  181 AVEHINRKRL LPGYTLELVT NDTQCDPGVG VDRFFHAIYT QPSTRMVMLL GSACSEVTES 240
  241 LAKVVPYWNI VQVSFGSTSP ALSDRREFPY FYRTVAPDSS HNPARIAFIR KFGWGTVTTF 300
  301 SQNEEVHSLA VNNLVTELEA ANISCAATIT FAATDFKEQL LLLRETDTRI IIGSFSQELA 360
  361 PQILCEAYRL RMFGADYAWI LHESMGAPWW PDQRTACSNH ELQLAVENLI VVSTHNSIVG 420
  421 NNVSYSGLNN HMFNSQLRKQ SAQFHGQDGF GSGYGSRISI AATQSDSRRR RRRGVGGTSG 480
  481 GHLFPEAISQ YAPQTYDAVW AIALALRAAE EHWRRNEEQS KLDGFDYTRS DMAWEFLQQM 540
  541 GKLHFLGVSG PVSFSGPDRV GTTAFYQIQR GLLEPVALYY PATDALDFRC PRCRPVKWHS 600
  601 GQVPIAKRVF KLRVATIAPL AFYTIATLSS VGIALAIAFL AFNLHFRKLK AIKLSSPKLS 660
  661 NITAVGCIFV YATVILLGLD HSTLPSAEDS FATVCTARVY LLSAGFSLAF GSMFAKTYRV 720
  721 HRIFTRTGSV FKDKMLQDIQ LILLVGGLLL VDALLVTLWV VTDPMERHLH NLTLEISATD 780
  781 RSVVYQPQVE VCRSQHTQTW LSVLYAYKGL LLVVGVYMAW ETRHVKIPAL NDSQYIGVSV 840
  841 YSVVITSAIV VVLANLISER VTLAFITITA LILTSTTATL CLLFIPKLHD IWARNDIIDP 900
  901 VIHSMGLKME CNTRRFVVDD RRELQYRVEV QNRVYKKEIQ ALDAEIRKLE RLLESGLTTT 960
  961 STTTSSSTSL LTGGGHLKPE LTVTSGISQT PAASKNRTPS ISGILPNLLL SVLPPVIPRA1020
 1021 SWPSAEYMQI PMRRSVTFAS QPQLEEACLP AQDLINLRLA HQQATEAKTG LINRLRGIFS1080
 1081 RTTSSNKGST ASLADQKGLK AAFKSHMGLF TRLIPSSQTA SCNAIYNNPN QDSIPSEASS1140
 1141 HPNGNHLKPI HRGSLTKSGT HLDHLTKDPN FLPIPTISGG EQGDQTLGGK YVKLLETKVN1200
 1201 FQLPSNRRPS VVQQPPSLRE RVRGSPRFPH RILPPTCSLS ALAESEDRPG DSTSILGSCK1260
 1261 SIPRISLQQA TSGGTWKSME TAGKSRLSLG DSQEEEQQAP ANGTE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FBpp0310352, FBp...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: