Protein Overview: AL1A1_RAT

General Information:
Name(s) found:	AL1A1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JC5553 aldehyde dehydrogenase (NAD) (EC 1.2.1.3) - rat [NCBI NR] gi\|38494348\|gb\|AAH61526.1\| Aldehyde dehydrogenase 1 family, member A1 [Rattus norvegicus] [NCBI NR] gi\|2183217\|gb\|AAC53306.1\| aldehyde dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|2183215\|gb\|AAC53305.1\| aldehyde dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|2183213\|gb\|AAC53304.1\| aldehyde dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|1916794\|gb\|AAB63423.1\| aldehyde dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|149062571\|gb\|EDM12994.1\| rCG47846 [Rattus norvegicus] [NCBI NR] gi\|14424442\|sp\|P51647.3\|AL1A1_RAT RecName: Full=Retinal dehydrogenase 1; Short=RALDH 1; Short=RalDH1; AltName: Full=Aldehyde dehydrogenase family 1 member A1; AltName: Full=Aldehyde dehydrogenase, cytosolic; AltName: Full=ALHDII; AltName: Full=ALDH-E1 [NCBI NR] gi\|14192935\|ref\|NP_071852.2\| aldehyde dehydrogenase 1A1 [Rattus norvegicus] [NCBI NR] Retinal dehydrogenase 1 OS=Rattus norvegicus GN=Aldh1a1 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):1-243991490 Aldehyde dehydrogenase 1A1 [hmr_yeast5_DM3-1_pombe.fasta] aldehyde dehydrogenase family 1, member A1; Aldehyde dehydrogenase 1; aldehyde dehydrogenase 1, subfamily A1; aldehyde dehydrogenase 2; Aldehyde dehydrogenase 1 subfamily A1 [HMR_022704-rand.fasta] aldehyde dehydrogenase family 1, member A1; aldehyde dehydrogenase 2; aldehyde dehydrogenase 1, subfamily A1; aldehyde dehydrogenase 1; Aldehyde dehydrogenase 1 subfamily A1 [071204_hmrz_cont.fasta] aldehyde dehydrogenase family 1, member A1 [Rattus norvegicus]gi\|38494348\|gb\|AAH61526.1\| Aldehyde dehydrogenase family 1, member A1 [Rattus norvegicus]gi\|14424442\|sp\|P51647\|DHA1_RAT Aldehyde dehydrogenase 1A1 (Aldehyde dehydrogenase, cytosolic) (ALDH cl [nrdb_11152004_Chlamydomonas] (NM_022407) Aldehyde dehydrogenase 1, subfamily A1; Aldehyde dehydrogenase 2; Aldehyde dehydrogenase 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Retinal dehydrogenase 1 (RALDH 1) (RalDH1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Aldehyde dehydrogenase family 1, subfamily A1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aldehyde dehydrogenase family 1, subfamily A1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG47846 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aldehyde dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ALDEHYDE DEHYDROGENASE FAMILY 1, MEMBER A1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] aldehyde dehydrogenase 1A1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Aldehyde dehydrogenase family 1, member A1 [Rattus norvegicus] [nr-271106-contam.fasta] aldehyde dehydrogenase family 1, member A1 [Rattus norvegicus] [nr-271106-contam.fasta] Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Aldh1a1 Retinal dehydrogenase 1 [rat-ipi-250309-contam.fasta] Retinal dehydrogenase 1 OS=Rattus norvegicus GN=Aldh1a1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	501 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] cytoplasm [IEA]
Biological Process:	midgut development [IEP] 9-cis-retinoic acid biosynthetic process [UNKNOWN][IEA] 9-cis-retinoic acid metabolic process [IDA] optic cup morphogenesis involved in camera-type eye development [UNKNOWN][IEA] retinol metabolic process [UNKNOWN][IEA] estrous cycle phase [IEP] retinoic acid metabolic process [UNKNOWN] response to organic cyclic substance [IEP] response to oxidative stress [IMP] response to ethanol [IDA] response to retinoic acid [IEP] protein homotetramerization [IDA] kidney development [IEP] embryonic eye morphogenesis [UNKNOWN][IEA] liver development [IEP] response to drug [UNKNOWN][IEP] positive regulation of apoptosis [UNKNOWN][IEA] response to estradiol stimulus [IEP] oxidation reduction [IEA]
Molecular Function:	aldehyde dehydrogenase (NAD) activity [IDA] 3-chloroallyl aldehyde dehydrogenase activity [UNKNOWN][TAS] identical protein binding [IDA] oxidoreductase activity [IEA] retinal dehydrogenase activity [IDA] benzaldehyde dehydrogenase (NAD+) activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPAQPAVP APLANLKIQH TKIFINNEWH DSVSGKKFPV LNPATEEVIC HVEEGDKADV  60
   61 DKAVKAARQA FQIGSPWRTM DASERGRLLN KLADLMERDR LLLATIEAIN GGKVFANAYL 120
  121 SDLGGSIKAL KYCAGWADKI HGQTIPSDGD IFTFTRREPI GVCGQIIPWN FPLLMFIWKI 180
  181 GPALSCGNTV VVKPAEQTPL TALHMASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMDVD 240
  241 KVAFTGSTQV GKLIKEAAGK SNLKRVTLEL GGKSPCIVFA DADLDIAVEF AHHGVFYHQG 300
  301 QCCVAASRIF VEESVYDEFV RKSVERAKKY VLGNPLTQGI NQGPQIDKEQ HDKILDLIES 360
  361 GKKEGAKLEC GGGRWGNKGF FVQPTVFSNV TDEMRIAKEE IFGPVQQIMK FKSIDDVIKR 420
  421 ANNTTYGLAA GVFTKDLDRA ITVSSALQAG VVWVNCYMIL SAQCPFGGFK MSGNGRELGE 480
  481 HGLYEYTELK TVAMKISQKN S

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.88

Protein Overview: AL1A1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: