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Protein Overview: AL1A1_RAT

General Information:
Name(s) found: AL1A1_RAT [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
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  • Retinal dehydrogenase 1 OS=Rattus norvegicus GN=Aldh1a1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 501 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    cytoplasm [IEA]
    Biological Process: midgut development [IEP]
    9-cis-retinoic acid biosynthetic process [UNKNOWN][IEA]
    9-cis-retinoic acid metabolic process [IDA]
    optic cup morphogenesis involved in camera-type eye development [UNKNOWN][IEA]
    retinol metabolic process [UNKNOWN][IEA]
    estrous cycle phase [IEP]
    retinoic acid metabolic process [UNKNOWN]
    response to organic cyclic substance [IEP]
    response to oxidative stress [IMP]
    response to ethanol [IDA]
    response to retinoic acid [IEP]
    protein homotetramerization [IDA]
    kidney development [IEP]
    embryonic eye morphogenesis [UNKNOWN][IEA]
    liver development [IEP]
    response to drug [UNKNOWN][IEP]
    positive regulation of apoptosis [UNKNOWN][IEA]
    response to estradiol stimulus [IEP]
    oxidation reduction [IEA]
    Molecular Function: aldehyde dehydrogenase (NAD) activity [IDA]
    3-chloroallyl aldehyde dehydrogenase activity [UNKNOWN][TAS]
    identical protein binding [IDA]
    oxidoreductase activity [IEA]
    retinal dehydrogenase activity [IDA]
    benzaldehyde dehydrogenase (NAD+) activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPAQPAVP APLANLKIQH TKIFINNEWH DSVSGKKFPV LNPATEEVIC HVEEGDKADV  60
   61 DKAVKAARQA FQIGSPWRTM DASERGRLLN KLADLMERDR LLLATIEAIN GGKVFANAYL 120
  121 SDLGGSIKAL KYCAGWADKI HGQTIPSDGD IFTFTRREPI GVCGQIIPWN FPLLMFIWKI 180
  181 GPALSCGNTV VVKPAEQTPL TALHMASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMDVD 240
  241 KVAFTGSTQV GKLIKEAAGK SNLKRVTLEL GGKSPCIVFA DADLDIAVEF AHHGVFYHQG 300
  301 QCCVAASRIF VEESVYDEFV RKSVERAKKY VLGNPLTQGI NQGPQIDKEQ HDKILDLIES 360
  361 GKKEGAKLEC GGGRWGNKGF FVQPTVFSNV TDEMRIAKEE IFGPVQQIMK FKSIDDVIKR 420
  421 ANNTTYGLAA GVFTKDLDRA ITVSSALQAG VVWVNCYMIL SAQCPFGGFK MSGNGRELGE 480
  481 HGLYEYTELK TVAMKISQKN S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle