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Protein Overview: MK_RAT

General Information:
Name(s) found: MK_RAT [Swiss-Prot]
Description(s) found:
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  • gi|5821356|dbj|BAA83783.1| midkine [Rattus norvegicus] [NCBI NR]
  • gi|57012883|sp|Q9R1S9.1|MK_RAT RecName: Full=Midkine; Short=MK; Flags: Precursor [NCBI NR]
  • gi|163915912|gb|AAI57806.1| Midkine [Rattus norvegicus] [NCBI NR]
  • gi|149022656|gb|EDL79550.1| midkine, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|149022655|gb|EDL79549.1| midkine, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|149022654|gb|EDL79548.1| midkine, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|13540681|ref|NP_110486.1| midkine [Rattus norvegicus] [NCBI NR]
  • gi|12007354|gb|AAG45151.1|AF315950_1 midkine [Rattus norvegicus] [NCBI NR]
  • Midkine OS=Rattus norvegicus GN=Mdk PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):3-69958265 MIDKINE [hmr_yeast5_DM3-1_pombe.fasta]
  • midkine [HMR_022704-rand.fasta]
  • midkine [Rattus norvegicus]gi|12007354|gb|AAG45151.1| midkine [Rattus norvegicus]gi|5821356|dbj|BAA83783.1| midkine [Rattus norvegicus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Midkine precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_030859) midkine [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • midkine [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Midkine precursor (MK) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Midkine [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • midkine, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 MIDKINE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Mdk Midkine [rat-ipi-250309-contam.fasta]
  • midkine precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Midkine OS=Rattus norvegicus GN=Mdk [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 140 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    Biological Process: M phase of mitotic cell cycle [IEP]
    positive regulation of cell division [IEA]
    multicellular organismal development [IEA]
    response to drug [IEP]
    response to glucocorticoid stimulus [IEP]
    response to wounding [IDA]
    cell differentiation [IEA]
    response to hormone stimulus [IEP]
    cell migration [IDA]
    adrenal gland development [IDA]
    Molecular Function: growth factor activity [IEA]
    heparin binding [UNKNOWN][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHRSFFLLA LVALLAVTTA VAKKKDKVKK GSECSEWTWG PCTPSSKDCG MGFREGTCGA  60
   61 QTQRIHCKVP CNWKKEFGAD CKYKFESWGA CDGSTGTKAR QGTLKKARYN AQCQETIRVT 120
  121 KPCTSKTKSK AKAKKGKGKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] FFAS03 4.17 Midkine, a heparin-binding growth factor, N-terminal domain
    2 View Details [79..140] Pfam 36.0 No description for PF01091.9 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle