Protein Overview: WNK4_RAT

General Information:
Name(s) found:	WNK4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|73920975\|sp\|Q7TPK6.3\|WNK4_RAT RecName: Full=Serine/threonine-protein kinase WNK4; AltName: Full=Protein kinase with no lysine 4; AltName: Full=Protein kinase, lysine-deficient 4 [NCBI NR] gi\|29468618\|gb\|AAO38858.1\| WNK4 Ser/Thr kinase [Rattus norvegicus] [NCBI NR] gi\|149054288\|gb\|EDM06105.1\| WNK lysine deficient protein kinase 4 [Rattus norvegicus] [NCBI NR] Serine/threonine-protein kinase WNK4 OS=Rattus norvegicus GN=Wnk4 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):10-88467488 WNK4 Ser/Thr kinase [hmr_yeast5_DM3-1_pombe.fasta] WNK4 Ser/Thr kinase [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Serine/threonine-protein kinase WNK4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 2 of Serine/threonine-protein kinase WNK4 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Serine/threonine-protein kinase WNK4 (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] WNK lysine deficient protein kinase 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 2 OF SERINE/THREONINE-PROTEIN KINASE WNK4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Vps25;Wnk4 Serine/threonine-protein kinase WNK4 [rat-ipi-250309-contam.fasta] Serine/threonine-protein kinase WNK4 OS=Rattus norvegicus GN=Wnk4 [011711_HMR.fasta] Serine/threonine-protein kinase WNK4 OS=Rattus norvegicus GN=Wnk4 PE=2 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1222 amino acids
Gene Ontology:
Cellular Component:	tight junction [ISS] cytoplasm [UNKNOWN][IEA] cell junction [IEA] cellular_component [ND]
Biological Process:	ion transport [ISS] regulation of cellular process [ISS] protein localization [UNKNOWN][IEA] intracellular protein kinase cascade [ISS] protein amino acid phosphorylation [IDA][ISS] chloride transport [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [ISS] protein binding [IPI] protein serine/threonine kinase activity [IDA][ISS] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAPRNTETG VHMSQTEADL ALRPSPSLTS MGPTRLGPPP RRVRRFSGKA EPRPRSSRPS  60
   61 RRSSVDLGLL SSWSQPASLL PEPPDPPDSA GPMRSPPSNS KEHPEGTWTG AAPVKAADSA 120
  121 CPELTVSSGG PGSREPPRVP DAAARERRRE QEEKEDTETQ AVATSPDGRY LKFDIEIGRG 180
  181 SFKTVYRGLD TDTTVEVAWC ELQTRKLSRA ERQRFSEEVE MLKGLQHPNI VRFYDSWKSV 240
  241 LRGQVCIVLV TELMTSGTLK TYLRRFREMK PRVLQRWSRQ ILRGLHFLHS RVPPILHRDL 300
  301 KCDNVFITGP SGSVKIGDLG LATLKRASFA KSVIGTPEFM APEMYEEKYD EAVDVYAFGM 360
  361 CMLEMATSEY PYSECQNAAQ IYRKVTSGTK PNSFYKVKMP EVKEIIEGCI RTDKNERFTI 420
  421 QDLLTHAFFR EERGVHVELA EEDDGEKPGL KLWLRMEDAR RGGRPRDNQA IEFLFQLGRD 480
  481 AAEEVAQEMV ALGLVCEADY QPVARAVRER VAAIQRKREK LRKARELEVL PPDSGPPPAT 540
  541 VSMTPGPPSA FPPEPEEPEA DQHQSFLFRH ASYSSTTSDC ETDGYLSSSG FLDASDPALQ 600
  601 PPGGMPSSPA EPHLCLPSGF ALSIPRSGPG SDFSPGDSYA SDAASGLSDM GEGGQMRKNP 660
  661 VKTLRRRPRS RLRVTSVSDQ SDRVVECQLQ THNSKMVTFR FDLDGDSPEE IAAAMVYNEF 720
  721 ILPSERDGFL SRIREIIQRV ETLLKRDAGP SEATEDALSP QEEPAAMPAL PGPSDAELQR 780
  781 SISPEQRSWA AFSTSPSSPG TPLSPGTPFS PGTPPVFPCP IFPITSPSCH PYPFSQVSSN 840
  841 PCPQAPSSLL PSSSGASQVP FPSPSLPTSS PLPFSPSYPQ VPLHPASLPT CPSPPPLPST 900
  901 TAAPLLSLAS AFSLAVMTVA QSLLSPSPGL LSQSPPAPPG PLPSMPLPLA SCDQESLSAQ 960
  961 TAETENEASR NPAQPLLGDA RLAPISEEGK PQLVGRFQVT SSKEPAEPPL QPASPTLSRS1020
 1021 LKLPTPQLTS ESSDTEDSAA GGPETREALA ESDRAAEGLG VAIDEEKDEG KEPQIGGSSP1080
 1081 ILSQPSPVWM NYSYSSLCLS SEESESSGED EEFWAELQNL RQKHLSEVEA LQTLQKKEIE1140
 1141 DLYSRLGKQP PPGIVAPAAM LSCRQRRLSK GSFPTSRRNS LQRSDLPGPG IMRRNSLSGS1200
 1201 STGSQEQRAS KGVTFAGDVG RM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.78

Protein Overview: WNK4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: