General Information: |
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Name(s) found: |
APEX1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 317 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[UNKNOWN][IDA][ISS]
transcription factor complex [IDA] centrosome [UNKNOWN] perinuclear region of cytoplasm [UNKNOWN][ISS] cytoplasm [UNKNOWN][IDA] mitochondrion [IDA] intracellular [IEA] nucleoplasm [UNKNOWN] |
Biological Process: |
DNA repair
[NAS]
regulation of DNA binding [UNKNOWN] positive regulation of S phase of mitotic cell cycle [IMP] response to drug [IEP] response to cAMP [IEP] negative regulation of smooth muscle cell migration [IMP] cell redox homeostasis [UNKNOWN][NAS] cellular response to hydrogen peroxide [IDA] aging [IDA] response to organic nitrogen [IEP] response to peptide hormone stimulus [IDA] |
Molecular Function: |
DNA binding
[UNKNOWN][ISS]
protein binding [UNKNOWN][IDA][IPI] transcription coactivator activity [UNKNOWN][ISS] oxidoreductase activity [UNKNOWN][ISS] transcription regulator activity [TAS] metal ion binding [UNKNOWN][ISS] endonuclease activity [UNKNOWN] lyase activity [IEA] DNA-(apurinic or apyrimidinic site) lyase activity [IEA] phosphoric diester hydrolase activity [UNKNOWN] protein complex binding [IPI] endoribonuclease activity [IDA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MPKRGKRAAA EDGEEPKSEP ETKKSKGAAK KTEKEAAGEG PVLYEDPPDQ KTSASGKSAT 60 61 LKICSWNVDG LRAWIKKKGL DWVKEEAPDI LCLQETKCSE NKLPAELQEL PGLTHQYWSA 120 121 PSDKEGYSGV GLLSRQCPLK VSYGIGEEEH DQEGRVIVAE FESFILVTAY VPNAGRGLVR 180 181 LEYRQRWDEA FRKFLKDLAS RKPLVLCGDL NVAHEEIDLR NPKGNKKNAG FTPQERQGFG 240 241 EMLQAVPLAD SFRHLYPNTA YAYTFWTYMM NARSKNVGWR LDYFLLSHSL LPALCDSKIR 300 301 SKALGSDHCP ITLYLAL |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)