Protein Overview: PFKAL_RAT

General Information:
Name(s) found:	PFKAL_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981352\|ref\|NP_037322.1\| phosphofructokinase, liver [Rattus norvegicus] [NCBI NR] gi\|56887\|emb\|CAA41674.1\| 6-phosphofructokinase [Rattus norvegicus] [NCBI NR] gi\|400095\|sp\|P30835.3\|K6PL_RAT RecName: Full=6-phosphofructokinase, liver type; AltName: Full=Phosphofructokinase 1; AltName: Full=Phosphohexokinase; AltName: Full=Phosphofructo-1-kinase isozyme B; Short=PFK-B [NCBI NR] pir\|\|S19689 6-phosphofructokinase (EC 2.7.1.11) - rat [NCBI NR] ATP-dependent 6-phosphofructokinase, liver type OS=Rattus norvegicus GN=Pfkl PE=1 SV=3 [Swiss-Prot] 6-phosphofructokinase, liver type OS=Rattus norvegicus GN=Pfkl PE=2 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):20-11805437 6-phosphofructokinase, liver type [hmr_yeast5_DM3-1_pombe.fasta] phosphofructokinase, liver, B-type [HMR_022704-rand.fasta] phosphofructokinase, liver, B-type [Rattus norvegicus]gi\|56887\|emb\|CAA41674.1\| 6-phosphofructokinase [Rattus norvegicus]gi\|400095\|sp\|P30835\|K6PL_RAT 6-phosphofructokinase, liver type (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase is [nrdb_11152004_Chlamydomonas] (NM_013190) phosphofructokinase, liver, B-type [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] 6-phosphofructokinase, liver type (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme B) (PFK-B) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphofructokinase, liver, B-type [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 6-phosphofructokinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphofructokinase, liver [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pfkl 6-phosphofructokinase, liver type [rat-ipi-250309-contam.fasta] 6-phosphofructokinase, liver type OS=Rattus norvegicus GN=Pfkl [011711_HMR.fasta] ATP-dependent 6-phosphofructokinase, liver type OS=Rattus norvegicus GN=Pfkl PE=2 SV=3 [20141208_RAT.fasta]
Organism:	Rattus norvegicus
Length:	780 amino acids
Gene Ontology:
Cellular Component:	6-phosphofructokinase complex [UNKNOWN] soluble fraction [IDA] cytosol [UNKNOWN][IDA]
Biological Process:	carbohydrate metabolic process [IDA] response to glucose stimulus [UNKNOWN] protein homotetramerization [IDA] glycolysis [UNKNOWN][IDA] fructose 6-phosphate metabolic process [UNKNOWN][IDA] negative regulation of insulin secretion [UNKNOWN] fructose 1,6-bisphosphate metabolic process [IDA] protein oligomerization [UNKNOWN]
Molecular Function:	ATP binding [UNKNOWN][IDA] identical protein binding [UNKNOWN] fructose binding [UNKNOWN] fructose-6-phosphate binding [UNKNOWN][IDA] fructose-2,6-bisphosphate 2-phosphatase activity [TAS] monosaccharide binding [IDA] 6-phosphofructokinase activity [UNKNOWN][IDA][TAS] kinase binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATVDLEKLR MSGAGKAIGV LTSGGDAQGM NAAVRAVTRM GIYVGAKVFL IYEGYEGLVE  60
   61 GGENIKPANW LSVSNIIQLG GTIIGSARCK AFTTREGRLA AAYNLLQHGI TNLCVIGGDG 120
  121 SLTGANIFRN EWGSLLEELV KEGKISESTA QNYAHLSIAG LVGSIDNDFC GTDMTIGTDS 180
  181 ALHRIMEVID AITTTAQSHQ RTFVLEVMGR HCGYLALVSA LASGADWLFI PEAPPEDGWE 240
  241 NFMCERLGET RSRGSRLNII IIAEGAIDRH GKPISSSYVK DLVVQRLGFD TRVTVLGHVQ 300
  301 RGGTPSAFDR VLSSKMGMEA VMALLEATPD TPACVVSLSG NQSVRLPLME CVQVTKDVQK 360
  361 AMDEKRFDEA IQLRGRSFEN NWKIYKLLAH QKVSKEKSNF SLAILNVGAP AAGMNAAVRS 420
  421 AVRTGISEGH TVYVVHDGFE GLAKGQVQEV GWHDVAGWLG RGGSMLGTKR TLPKPHLEAI 480
  481 VENLRTYNIH ALLVIGGFEA YEGVLQLVEA RGRYEELCIV MCVIPATISN NVPGTDFSLG 540
  541 SDTAVNAAME SCDRIKQSAS GTKRRVFIVE TMGGYCGYLA TVTGIAVGAD AAYVFEDPFN 600
  601 IHDLKANVEH MTEKMKTDIQ RGLVLRNEKC HEHYTTEFLY NLYSSEGRGV FDCRTNVLGH 660
  661 LQQGGAPTPF DRNYGTKLGV KAMLWMSEKL RDVYRKGRVF ANAPDSACVI GLRKKVVAFS 720
  721 SVTELKKETD FEHRMPREQW WLNLRLMLKM LAHYRISMAD YVSGELEHVT RRTLSIDKGF 780
  781

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.79

Protein Overview: PFKAL_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: