Protein Overview: SOCS1_RAT

General Information:
Name(s) found:	SOCS1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6625503\|emb\|CAB64204.1\| suppressor of cytokine signalling 1 [Rattus norvegicus] [NCBI NR] gi\|22024396\|ref\|NP_665886.1\| suppressor of cytokine signaling 1 [Rattus norvegicus] [NCBI NR] gi\|20178091\|sp\|Q9QX78.1\|SOCS1_RAT RecName: Full=Suppressor of cytokine signaling 1; Short=SOCS-1 [NCBI NR] Suppressor of cytokine signaling 1 OS=Rattus norvegicus GN=Socs1 PE=3 SV=1 [Swiss-Prot] (Q9QX78) Suppressor of cytokine signaling 1 (SOCS-1) [Swiss-Prot] Ensembl_locations(Chr-bp):10-2885306 Suppressor of cytokine signaling 1 [hmr_yeast5_DM3-1_pombe.fasta] cytokine inducible SH2-containing protein 1 [HMR_022704-rand.fasta] suppressor of cytokine signaling 1; cytokine inducible SH2-containing protein 1 [071204_hmrz_cont.fasta] suppressor of cytokine signaling 1 [Rattus norvegicus]gi\|6625503\|emb\|CAB64204.1\| suppressor of cytokine signalling 1 [Rattus norvegicus]gi\|20178091\|sp\|Q9QX78\|SOC1_RAT Suppressor of cytokine signaling 1 (SOCS-1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Suppressor of cytokine signaling 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_145879) cytokine inducible SH2-containing protein 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Suppressor of cytokine signaling 1 (SOCS-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] suppressor of cytokine signaling 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] suppressor of cytokine signalling 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SUPPRESSOR OF CYTOKINE SIGNALING 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Socs1 Suppressor of cytokine signaling 1 [rat-ipi-250309-contam.fasta] Suppressor of cytokine signaling 1 OS=Rattus norvegicus GN=Socs1 [011711_HMR.fasta] Suppressor of cytokine signaling 1 OS=Rattus norvegicus GN=Socs1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	212 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	response to cytokine stimulus [IEP] negative regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IEA] response to progesterone stimulus [IEP] fat cell differentiation [UNKNOWN][IEA] regulation of growth [IEA] response to peptide hormone stimulus [IEP] negative regulation of insulin receptor signaling pathway [UNKNOWN][IEA] negative regulation of JAK-STAT cascade [UNKNOWN][IEA] JAK-STAT cascade [UNKNOWN] negative regulation of signal transduction [IEA] regulation of protein amino acid phosphorylation [UNKNOWN][IEA] cytokine-mediated signaling pathway [UNKNOWN][IEA] response to drug [IEP] response to estradiol stimulus [IEP] response to lipopolysaccharide [IEP] organ regeneration [IEP]
Molecular Function:	protein kinase binding [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] kinase inhibitor activity [UNKNOWN][IEA] molecular_function [ND] insulin-like growth factor receptor binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVARNQVAAD NAISPASEPR RRPEPSSSSS SSSPAAPRRP RPCPVVPAPA PGDTHFRTFR  60
   61 SHSDYRRITR TSALLDACGF YWGPLSVHGA HERLRAEPVG TFLVRDSRQR NCFFALSVKM 120
  121 ASGPTSIRVH FQAGRFHLDG SRETFDCLFE LLEHYVAAPR RMLGAPLRQR RVRPLQELCR 180
  181 QRIVAAVGRE NLARIPLNPV LRDYLSSFPF QI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: SOCS1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: