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Protein Overview: SOCS1_RAT

General Information:
Name(s) found: SOCS1_RAT [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Suppressor of cytokine signaling 1 OS=Rattus norvegicus GN=Socs1 PE=3 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 212 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: response to cytokine stimulus [IEP]
    negative regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IEA]
    response to progesterone stimulus [IEP]
    fat cell differentiation [UNKNOWN][IEA]
    regulation of growth [IEA]
    response to peptide hormone stimulus [IEP]
    negative regulation of insulin receptor signaling pathway [UNKNOWN][IEA]
    negative regulation of JAK-STAT cascade [UNKNOWN][IEA]
    JAK-STAT cascade [UNKNOWN]
    negative regulation of signal transduction [IEA]
    regulation of protein amino acid phosphorylation [UNKNOWN][IEA]
    cytokine-mediated signaling pathway [UNKNOWN][IEA]
    response to drug [IEP]
    response to estradiol stimulus [IEP]
    response to lipopolysaccharide [IEP]
    organ regeneration [IEP]
    Molecular Function: protein kinase binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA]
    kinase inhibitor activity [UNKNOWN][IEA]
    molecular_function [ND]
    insulin-like growth factor receptor binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVARNQVAAD NAISPASEPR RRPEPSSSSS SSSPAAPRRP RPCPVVPAPA PGDTHFRTFR  60
   61 SHSDYRRITR TSALLDACGF YWGPLSVHGA HERLRAEPVG TFLVRDSRQR NCFFALSVKM 120
  121 ASGPTSIRVH FQAGRFHLDG SRETFDCLFE LLEHYVAAPR RMLGAPLRQR RVRPLQELCR 180
  181 QRIVAAVGRE NLARIPLNPV LRDYLSSFPF QI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle