Protein Overview: GREM1_RAT

General Information:
Name(s) found:	GREM1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9506493\|ref\|NP_062155.1\| gremlin 1 homolog, cysteine knot superfamily [Rattus norvegicus] [NCBI NR] gi\|62510533\|sp\|O35793.1\|GREM1_RAT RecName: Full=Gremlin-1; AltName: Full=Cysteine knot superfamily 1, BMP antagonist 1; AltName: Full=Down-regulated in Mos-transformed cells protein; Flags: Precursor [NCBI NR] gi\|2288921\|emb\|CAA71126.1\| DRM protein [Rattus norvegicus] [NCBI NR] gi\|149022923\|gb\|EDL79817.1\| rCG26386 [Rattus norvegicus] [NCBI NR] gi\|149022922\|gb\|EDL79816.1\| gremlin 1 homolog, cysteine knot superfamily (Xenopus laevis) [Rattus norvegicus] [NCBI NR] Gremlin-1 OS=Rattus norvegicus GN=Grem1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None DRM protein [hmr_yeast5_DM3-1_pombe.fasta] cysteine knot superfamily 1, BMP antagonist 1 [HMR_022704-rand.fasta] cysteine knot superfamily 1, BMP antagonist 1 [Rattus norvegicus]gi\|2288921\|emb\|CAA71126.1\| DRM protein [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Gremlin-1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_019282) cysteine knot superfamily 1, BMP antagonist 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] gremlin 1 homolog, cysteine knot superfamily [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG26386 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] gremlin 1 homolog, cysteine knot superfamily (Xenopus laevis) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] DRM protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 DRM PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Grem1 Gremlin-1 [rat-ipi-250309-contam.fasta] Gremlin-1 OS=Rattus norvegicus GN=Grem1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	184 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IDA] extracellular region [IEA] cell surface [IDA]
Biological Process:	cell-cell signaling [UNKNOWN][IEA] positive regulation of NF-kappaB import into nucleus [UNKNOWN] positive regulation of NF-kappaB transcription factor activity [UNKNOWN] proximal/distal pattern formation [UNKNOWN][IEA] organ morphogenesis [UNKNOWN][IEA] negative regulation of BMP signaling pathway [UNKNOWN][IEA] regulation of epithelial to mesenchymal transition [UNKNOWN] embryonic limb morphogenesis [UNKNOWN][IEA] negative regulation of leukocyte chemotaxis [IDA] angiogenesis [UNKNOWN] negative regulation of cell growth [IMP] branching involved in ureteric bud morphogenesis [UNKNOWN][IEA] apoptosis [IEP]
Molecular Function:	protein binding [UNKNOWN][IDA][IPI] cytokine activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRTAYTVGA LLLLLGTLLP AAEGKKKGSQ GAIPPPDKAQ HNDSEQTQSP PQPGSRTRGR  60
   61 GQGRGTAMPG EEVLESSQEA LHVTERKYLK RDWCKTQPLK QTIHEEGCNS RTIINRFCYG 120
  121 QCNSFYIPRH IRKEEGSFQS CSFCKPKKFT TMMVTLNCPE LQPPTKKKRV TRVKQCRCIS 180
  181 IDLD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GREM1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: