Protein Overview: NR5A2_RAT

General Information:
Name(s) found:	NR5A2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81907060\|sp\|Q9QWM1.1\|NR5A2_RAT RecName: Full=Nuclear receptor subfamily 5 group A member 2; AltName: Full=Liver receptor homolog 1; Short=LRH-1; AltName: Full=FTZ-F1 beta [NCBI NR] gi\|4107117\|dbj\|BAA36339.1\| FTZ-F1 beta1 [Rattus norvegicus] [NCBI NR] gi\|13492975\|ref\|NP_068510.1\| FTZ-F1 beta1 protein [Rattus norvegicus] [NCBI NR] Nuclear receptor subfamily 5 group A member 2 OS=Rattus norvegicus GN=Nr5a2 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):13-105068162 FTZ-F1 beta1 [hmr_yeast5_DM3-1_pombe.fasta] FTZ-F1 beta1 protein; FTZ-F1 beta; FTZ-F1 beta2 protein; fetoprotein transcription factor [HMR_022704-rand.fasta] FTZ-F1 beta1 protein; FTZ-F1 beta; FTZ-F1 beta2 protein; fetoprotein transcription factor; liver receptor homolog 1 [071204_hmrz_cont.fasta] FTZ-F1 beta1 protein [Rattus norvegicus]gi\|4107117\|dbj\|BAA36339.1\| FTZ-F1 beta1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Orphan nuclear receptor NR5A2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 FTZ-F1 beta1 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_021742) FTZ-F1 beta1 protein; FTZ-F1 beta; FTZ-F1 beta2 protein [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Nuclear receptor subfamily 5 group A member 2 (Liver receptor homolog 1) (LRH-1) (FTZ-F1 beta) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] FTZ-F1 beta1 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] FTZ-F1 beta1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 FTZ-F1 BETA1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1) (FTZ-F1 beta) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Nr5a2 Isoform 1 of Nuclear receptor subfamily 5 group A member 2 [rat-ipi-250309-contam.fasta] Isoform 1 of Nuclear receptor subfamily 5 group A member 2 OS=Rattus norvegicus GN=Nr5a2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	560 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] cytoplasm [UNKNOWN][IEA]
Biological Process:	regulation of transcription, DNA-dependent [IEA] positive regulation of transcription [UNKNOWN][IEA] positive regulation of viral genome replication [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] bile acid metabolic process [UNKNOWN][IEA] cholesterol homeostasis [UNKNOWN][IEA] regulation of cell proliferation [UNKNOWN][IEA]
Molecular Function:	DNA binding [UNKNOWN] transcription factor activity [UNKNOWN][IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] ligand-dependent nuclear receptor activity [IDA] metal ion binding [IEA] steroid hormone receptor activity [IEA] lipid binding [IEA] sequence-specific DNA binding [UNKNOWN] promoter binding [UNKNOWN][IEA] transcription activator activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASSITGDF QDFLKHGLPA IAPAPGSETP HSPKLEEKHR EKRAGLPDRH RRPIPARSRL  60
   61 VMLPKVETEA SGLVRSHGEQ GQMPENMQVS QFKMVNYSYD EDLEELCPVC GDKVSGYHYG 120
  121 LLTCESCKGF FKRTVQNQKR YTCIENQNCQ IDKTQRKRCP YCRFKKCIDV GMKLEAVRAD 180
  181 RMRGGRNKFG PMYKRDRALK QQKKALIRAN GLKLEAMSQV IQAMPSDLTS AIQNIHSASK 240
  241 GLPLSHVALP PTDYDRSPFV TSPISMTMPP HGSLHGYQPY GHFPNRAIKS EYPDPYSSSP 300
  301 ESMMGYSYMD GYQTSSPASI PHLILELLKC EPDEPQVQAK IMAYLQQEQN NRNRQEKLSA 360
  361 FGLLCKMADQ TLFSIVEWAR SSIFFRELKV DDQMKLLQNC WSELLILDHI YRQVAHGKEG 420
  421 TIFLVTGEHV DYSSIISNTE VAFNNLLSLA QELVVRLRSL QFDQREFVCL KFLVLFSSDV 480
  481 KNLENFQLVE GVQEQVNAAL LDYTLCNYPQ QTEKFGQLLL RLPEIRAISK QAEDYLYYKH 540
  541 VNGDVPYNNL LIEMLHAKRA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: NR5A2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: