Protein Overview: NKX61_RAT

General Information:
Name(s) found:	NKX61_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|62660098\|ref\|XP_579527.1\| PREDICTED: NK6 transcription factor related, locus 1 [Rattus norvegicus] [NCBI NR] gi\|6016213\|sp\|O35762.1\|NKX61_RAT RecName: Full=Homeobox protein Nkx-6.1 [NCBI NR] gi\|2218137\|gb\|AAB61665.1\| homeodomain protein Nkx6.1 [Rattus norvegicus] [NCBI NR] gi\|149046765\|gb\|EDL99539.1\| rCG37924, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13929036\|ref\|NP_113925.1\| NK6 homeobox 1 [Rattus norvegicus] [NCBI NR] Homeobox protein Nkx-6.1 OS=Rattus norvegicus GN=Nkx6-1 PE=2 SV=1 [Swiss-Prot] (O35762) Homeobox protein Nkx-6.1 [Swiss-Prot] Ensembl_locations(Chr-bp):14-6870055 Homeobox protein Nkx-6.1 [hmr_yeast5_DM3-1_pombe.fasta] NK homeobox (Drosophila), family 6, A; NK6 transcription factor related, locus 1 (Drosophila); NK6 transcription factor homolog A (Drosophila); NK6 transcription factor related locus 1 (Drosophila) [HMR_022704-rand.fasta] NK homeobox (Drosophila), family 6, A; NK6 transcription factor homolog A (Drosophila); NK6 transcription factor related locus 1 (Drosophila); NK6 transcription factor related, locus 1 (Drosophila) [071204_hmrz_cont.fasta] NK homeobox (Drosophila), family 6, A [Rattus norvegicus]gi\|2218137\|gb\|AAB61665.1\| homeodomain protein Nkx6.1 [Rattus norvegicus]gi\|6016213\|sp\|O35762\|NK61_RAT Homeobox protein Nkx-6.1 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Homeobox protein Nkx-6.1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031737) NK homeobox (Drosophila), family 6, A; NK6 transcription factor related, locus 1 (Drosophila); NK6 transcription factor homolog A (Drosophila) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Homeobox protein Nkx-6.1 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] NK6 transcription factor related, locus 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG37924, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] homeodomain protein Nkx6.1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HOMEOBOX PROTEIN NKX-6.1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] NK6 homeobox 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Nkx6-1 Homeobox protein Nkx-6.1 [rat-ipi-250309-contam.fasta] Homeobox protein Nkx-6.1 OS=Rattus norvegicus GN=Nkx6-1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	365 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] intracellular part [UNKNOWN][IEA]
Biological Process:	oligodendrocyte differentiation [UNKNOWN][IEA] multicellular organismal development [IEA] regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification [UNKNOWN][IEA] regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification [UNKNOWN][IEA] cell differentiation [UNKNOWN][IEA] positive regulation of glial cell differentiation [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IEA] smoothened signaling pathway [UNKNOWN][IEA] positive regulation of neuron differentiation [UNKNOWN][IEA] positive regulation of insulin secretion [IMP] negative regulation of glial cell differentiation [UNKNOWN][IEA] endocrine pancreas development [UNKNOWN][IEA]
Molecular Function:	transcription factor activity [IDA] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAVGAMEGP RQSAFLLSSP PLAALHSMAE MKTPLYPAAY PPLPTGPPSS SSSSSSSSSP  60
   61 SPPLGAHNPG GLKPPAAGGL SSLGSPPQQL SAATPHGIND ILSRPSMPVA SGAALPSASP 120
  121 SGSSSSSSSS ASATSASAAA AAAAAAAAAA ASSPAGLLAG LPRFSSLSPP PPPPGLYFSP 180
  181 SAAAVAAVGR YPKPLAELPG RTPIFWPGVM QSPPWRDARL ACTPHQGSIL LDKDGKRKHT 240
  241 RPTFSGQQIF ALEKTFEQTK YLAGPERARL AYSLGMTESQ VKVWFQNRRT KWRKKHAAEM 300
  301 ATAKKKQDSE TERLKGTSEN EEDDDDYNKP LDPNSDDEKI TQLLKKHKSS GGSLLLHASE 360
  361 AEGSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NKX61_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: