Protein Overview: LIMK1_RAT

General Information:
Name(s) found:	LIMK1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|I58353 LIM protein kinase (EC 2.7.1.-) 1 [similarity] - rat [NCBI NR] gi\|1708822\|sp\|P53669.1\|LIMK1_RAT RecName: Full=LIM domain kinase 1; Short=LIMK-1 [NCBI NR] gi\|13929022\|ref\|NP_113915.1\| LIM motif-containing protein kinase 1 [Rattus norvegicus] [NCBI NR] gi\|1000682\|dbj\|BAA06672.1\| LIMK-1 [Rattus norvegicus] [NCBI NR] LIM domain kinase 1 OS=Rattus norvegicus GN=Limk1 PE=1 SV=1 [Swiss-Prot] (P53669) LIM domain kinase 1 (EC 2.7.1.37) (LIMK-1) [Swiss-Prot] Ensembl_locations(Chr-bp):12-23239030 LIM domain kinase 1 [hmr_yeast5_DM3-1_pombe.fasta] LIM motif-containing protein kinase 1; LIM-domain containing, protein kinase 1; LIM-domain containing, protein kinase; LIM-domain containing protein kinase 1; LIM-domain containing protein kinase [HMR_022704-rand.fasta] LIM motif-containing protein kinase 1; LIM-domain containing protein kinase 1; LIM-domain containing protein kinase; LIM-domain containing, protein kinase 1; LIM-domain containing, protein kinase [071204_hmrz_cont.fasta] LIM motif-containing protein kinase 1 [Rattus norvegicus]gi\|1708822\|sp\|P53669\|LIK1_RAT LIM domain kinase 1 (LIMK-1)gi\|2143832\|pir\|\|I58353 LIM protein kinase (EC 2.7.1.-) 1 [similarity] - ratgi\|1000682\|dbj\|BAA06672.1\| LIMK-1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 LIM domain kinase 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031727) LIM motif-containing protein kinase 1; LIM-domain containing, protein kinase 1; LIM-domain containing, protein kinase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] LIM domain kinase 1 (LIMK-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] LIMK-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 LIM DOMAIN KINASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] LIM motif-containing protein kinase 1 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Limk1 LIM domain kinase 1 [rat-ipi-250309-contam.fasta] LIM domain kinase 1 OS=Rattus norvegicus GN=Limk1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	647 amino acids
Gene Ontology:
Cellular Component:	growth cone [IEA] nucleus [UNKNOWN][IEA] focal adhesion [UNKNOWN][IEA] cytoplasm [UNKNOWN][IEA] cell projection [IEA]
Biological Process:	negative regulation of ubiquitin-protein ligase activity [UNKNOWN] positive regulation of axon extension [UNKNOWN][IEA] positive regulation of actin filament bundle assembly [UNKNOWN] protein amino acid phosphorylation [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] heat shock protein binding [UNKNOWN] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] metal ion binding [IEA] protein heterodimerization activity [UNKNOWN][IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLTLLCCTW REERMGEEGS ELPVCASCSQ SIYDGQYLQA LNADWHADCF RCCECSTSLS  60
   61 HQYYEKDGQL FCKKDYWARY GESCHGCSEH ITKGLVMVGG ELKYHPECFI CLACGNFIGD 120
  121 GDTYTLVEHS KLYCGQCYYQ TVVTPVIEQI LPDSPGSHLP HTVTLVSIPA SAHGKRGLSV 180
  181 SIDPPHGPPG CGTEHSHTVR VQGVDPGCMS PDVKNSIHIG DRILEINGTP IRNVPLDEID 240
  241 LLIQETSRLL QLTLEHDPHD SLGHGPVSDP SPLASPVHTP SGQAGSSARQ KPVLRSCSID 300
  301 TSPGAGSLVS PASQRKDLGR SESLRVVCRP HRIFRPSDLI HGEVLGKGCF GQAIKVTHRE 360
  361 TGEVMVMKEL IRFDEETQRT FLKEVKVMRC LEHPNVLKFI GVLYKDKRLN FITEYIKGGT 420
  421 LRGIIKSMDS QYPWSQRVSF AKDIASGMAY LHSMNIIHRD LNSHNCLVRE NRNVVVADFG 480
  481 LARLMIDEKG QSEDLRSLKK PDRKKRYTVV GNPYWMAPEM INGRSYDEKV DVFSFGIVLC 540
  541 EIIGRVNADP DYLPRTMDFG LNVRGFLDRY CPPNCPPSFF PITVRCCDLD PEKRPSFVKL 600
  601 EQWLETLRMH LAGHLPLGPQ LEQLERGFWE TYRRGESSLP AHPEVPD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: LIMK1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: