Protein Overview: TGFA_RAT

General Information:
Name(s) found:	TGFA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981646\|ref\|NP_036803.1\| transforming growth factor alpha [Rattus norvegicus] [NCBI NR] gi\|2851520\|sp\|P01134.2\|TGFA_RAT RecName: Full=Protransforming growth factor alpha; Contains: RecName: Full=Transforming growth factor alpha; Short=TGF-alpha; AltName: Full=EGF-like TGF; Short=ETGF; AltName: Full=TGF type 1; Flags: Precursor [NCBI NR] pir\|\|I57497 transforming growth factor alpha precursor - rat [NCBI NR] gi\|207282\|gb\|AAA42233.1\| transforming growth factor alpha precursor [NCBI NR] gi\|149036605\|gb\|EDL91223.1\| transforming growth factor alpha, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149036604\|gb\|EDL91222.1\| transforming growth factor alpha, isoform CRA_a [Rattus norvegicus] [NCBI NR] Protransforming growth factor alpha OS=Rattus norvegicus GN=Tgfa PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):4-124002423 Transforming growth factor alpha precursor [hmr_yeast5_DM3-1_pombe.fasta] transforming growth factor alpha; Transforming growth factor, alpha [HMR_022704-rand.fasta] transforming growth factor alpha [Rattus norvegicus]gi\|2851520\|sp\|P01134\|TGFA_RAT Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)gi\|2144001\|pir\|\|I57497 transforming growth factor alpha precursor - ratgi\|207282\| [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Transforming growth factor alpha precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012671) transforming growth factor, alpha [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Protransforming growth factor alpha precursor [Contains: Transforming growth factor alpha (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1)] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transforming growth factor alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transforming growth factor alpha, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transforming growth factor alpha precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1) [nr-271106-contam.fasta] Protransforming growth factor alpha OS=Rattus norvegicus GN=Tgfa [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	159 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] integral to plasma membrane [TAS] extracellular space [UNKNOWN][IDA] extracellular region [IEA] plasma membrane [IDA] cell surface [UNKNOWN]
Biological Process:	neuroprotection [IMP] epidermal growth factor receptor signaling pathway [TAS] positive regulation of cell proliferation [IMP] cytosolic calcium ion homeostasis [IMP] positive regulation of epidermal growth factor receptor activity [UNKNOWN][ISS] positive regulation of mitosis [UNKNOWN][ISS] negative regulation of cellular process [IDA] negative regulation of neuron apoptosis [IMP] activation of MAPK activity [UNKNOWN][ISS] wound healing [IEP] anti-apoptosis [IDA] positive regulation of cell division [IEA] mammary gland alveolus development [UNKNOWN][IEA] angiogenesis [UNKNOWN][IEA] response to drug [IEP] positive regulation of protein amino acid phosphorylation [IMP] positive regulation of epithelial cell proliferation [UNKNOWN][ISS]
Molecular Function:	growth factor activity [UNKNOWN][ISS][TAS] protein binding [UNKNOWN] MAP kinase kinase activity [UNKNOWN][ISS] epidermal growth factor receptor binding [UNKNOWN][IDA][ISS][TAS] glycoprotein binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPAAGQLAL LALGILVAVC QALENSTSPL SDSPVAAAVV SHFNKCPDSH TQYCFHGTCR  60
   61 FLVQEEKPAC VCHSGYVGVR CEHADLLAVV AASQKKQAIT ALVVVSIVAL AVLIITCVLI 120
  121 HCCQVRKHCE WCRALVCRHE KPSALLKGRT ACCHSETVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TGFA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: