Protein Overview: SOCS3_RAT

General Information:
Name(s) found:	SOCS3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|3319324\|gb\|AAC26223.1\| suppressor of cytokine signaling-3 [Rattus norvegicus] [NCBI NR] gi\|20178090\|sp\|O88583.1\|SOCS3_RAT RecName: Full=Suppressor of cytokine signaling 3; Short=SOCS-3; AltName: Full=Cytokine-inducible SH2 protein 3 [NCBI NR] gi\|16758336\|ref\|NP_446017.1\| suppressor of cytokine signaling 3 [Rattus norvegicus] [NCBI NR] Suppressor of cytokine signaling 3 OS=Rattus norvegicus GN=Socs3 PE=1 SV=1 [Swiss-Prot] (O88583) Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) [Swiss-Prot] Ensembl_locations(Chr-bp):10-105705844 Suppressor of cytokine signaling 3 [hmr_yeast5_DM3-1_pombe.fasta] cytokine inducible SH2-containing protein 3 [HMR_022704-rand.fasta] suppressor of cytokine signaling 3 [Rattus norvegicus]gi\|3319324\|gb\|AAC26223.1\| suppressor of cytokine signaling-3 [Rattus norvegicus]gi\|20178090\|sp\|O88583\|SOC3_RAT Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Suppressor of cytokine signaling 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053565) cytokine inducible SH2-containing protein 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] suppressor of cytokine signaling 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] suppressor of cytokine signaling-3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SUPPRESSOR OF CYTOKINE SIGNALING 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Socs3 Suppressor of cytokine signaling 3 [rat-ipi-250309-contam.fasta] Suppressor of cytokine signaling 3 OS=Rattus norvegicus GN=Socs3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	225 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	response to food [IEP] response to cytokine stimulus [IEP] response to progesterone stimulus [IEP] JAK-STAT cascade [IDA][TAS] response to heat [IEP] response to hypoxia [IEP] negative regulation of signal transduction [UNKNOWN][IEA] response to insulin stimulus [IEP] regulation of cell differentiation [UNKNOWN] trophoblast giant cell differentiation [UNKNOWN][IEA] response to glucocorticoid stimulus [IEP] spongiotrophoblast differentiation [UNKNOWN][IEA] response to gamma radiation [IEP] placenta blood vessel development [UNKNOWN][IEA] signal transduction [IDA][TAS] branching involved in embryonic placenta morphogenesis [UNKNOWN][IEA] intracellular protein kinase cascade [IDA] positive regulation of cell differentiation [UNKNOWN][IEA] response to organic cyclic substance [IEP] aging [IEP] response to hormone stimulus [IEP] response to peptide hormone stimulus [IEP] negative regulation of insulin receptor signaling pathway [UNKNOWN][IEA] response to bacterium [IEP] regulation of cell growth [TAS] regulation of protein amino acid phosphorylation [UNKNOWN][IEA] response to drug [IEP] response to estradiol stimulus [IEP] response to lipopolysaccharide [IEP] organ regeneration [IEP]
Molecular Function:	protein binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL  60
   61 SAEPAGTFLI RDSSDQRHFF TLSVETQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120
  121 LKLVHHYMPP PGAPSFSLPP TEPSFEVQEQ PPAQALPGGT PKRAYYIYSG GEKIPLVLSR 180
  181 PLSSNVATLQ HLCRKTVNGH LDSYEKVTQL PGPIREFLDQ YDAPL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: SOCS3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: