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Protein Overview: SOCS3_RAT

General Information:
Name(s) found: SOCS3_RAT [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Suppressor of cytokine signaling 3 OS=Rattus norvegicus GN=Socs3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 225 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    Biological Process: response to food [IEP]
    response to cytokine stimulus [IEP]
    response to progesterone stimulus [IEP]
    JAK-STAT cascade [IDA][TAS]
    response to heat [IEP]
    response to hypoxia [IEP]
    negative regulation of signal transduction [UNKNOWN][IEA]
    response to insulin stimulus [IEP]
    regulation of cell differentiation [UNKNOWN]
    trophoblast giant cell differentiation [UNKNOWN][IEA]
    response to glucocorticoid stimulus [IEP]
    spongiotrophoblast differentiation [UNKNOWN][IEA]
    response to gamma radiation [IEP]
    placenta blood vessel development [UNKNOWN][IEA]
    signal transduction [IDA][TAS]
    branching involved in embryonic placenta morphogenesis [UNKNOWN][IEA]
    intracellular protein kinase cascade [IDA]
    positive regulation of cell differentiation [UNKNOWN][IEA]
    response to organic cyclic substance [IEP]
    aging [IEP]
    response to hormone stimulus [IEP]
    response to peptide hormone stimulus [IEP]
    negative regulation of insulin receptor signaling pathway [UNKNOWN][IEA]
    response to bacterium [IEP]
    regulation of cell growth [TAS]
    regulation of protein amino acid phosphorylation [UNKNOWN][IEA]
    response to drug [IEP]
    response to estradiol stimulus [IEP]
    response to lipopolysaccharide [IEP]
    organ regeneration [IEP]
    Molecular Function: protein binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL  60
   61 SAEPAGTFLI RDSSDQRHFF TLSVETQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120
  121 LKLVHHYMPP PGAPSFSLPP TEPSFEVQEQ PPAQALPGGT PKRAYYIYSG GEKIPLVLSR 180
  181 PLSSNVATLQ HLCRKTVNGH LDSYEKVTQL PGPIREFLDQ YDAPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle