Protein Overview: TIM_RAT

General Information:
Name(s) found:	TIM_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T13959 timeless protein TIM - rat [NCBI NR] gi\|61216883\|sp\|Q9Z2Y1.1\|TIM_RAT RecName: Full=Protein timeless homolog; Short=rTIM; AltName: Full=Timeless-like protein; Short=rTLP [NCBI NR] gi\|3869211\|dbj\|BAA34400.1\| rTIM [Rattus norvegicus] [NCBI NR] gi\|13786174\|ref\|NP_112630.1\| timeless homolog [Rattus norvegicus] [NCBI NR] Protein timeless homolog OS=Rattus norvegicus GN=Timeless PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):13-1507512 RTIM [hmr_yeast5_DM3-1_pombe.fasta] timeless homolog [HMR_022704-rand.fasta] timeless homolog [Rattus norvegicus]gi\|7514104\|pir\|\|T13959 timeless protein TIM - ratgi\|3869211\|dbj\|BAA34400.1\| rTIM [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Timeless homolog [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031340) timeless (Drosophila) homolog [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Protein timeless homolog (rTIM) (Timeless-like protein) (rTLP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] timeless homolog [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rTIM [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 RTIM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Timeless homolog (rTIM) (Timeless-like protein) (rTLP) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Timeless Protein timeless homolog [rat-ipi-250309-contam.fasta] protein timeless homolog [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Protein timeless homolog OS=Rattus norvegicus GN=Timeless [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1205 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] nuclear chromatin [UNKNOWN]
Biological Process:	embryonic development [UNKNOWN] regulation of S phase [UNKNOWN] multicellular organismal development [IEA] mitosis [IEA] branching morphogenesis of a tube [UNKNOWN] response to DNA damage stimulus [IEA] circadian rhythm [UNKNOWN][ISS] positive regulation of circadian rhythm [IMP] cell cycle [IEA] [NOT]regulation of cell proliferation [UNKNOWN] cell division [IEA] kidney development [IMP] morphogenesis of an epithelium [UNKNOWN][IEP] branching involved in ureteric bud morphogenesis [IMP] negative regulation of transcription [UNKNOWN][ISS] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] lung development [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN][IPI] protein homodimerization activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI  60
   61 LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDPTVRHHF LQVLTYLQAY 120
  121 KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKRID 180
  181 DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQK PEQLAGVGQG 240
  241 RLAQERSTDL AELEVLRQRE VAEKRARALQ RGNRHSRFGG SYVVQGLKSI GERDVVFHKG 300
  301 LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA 360
  361 VKDHLLREKA QQHDETYYMW AMAFFMAFNR AAAFRPGFVS ETLSIRTFHF VEQNLTNYYE 420
  421 MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDDA VRESSRIIKN NIFYMMEYRE 480
  481 LFLALFRKFD ERYHPRSFLC DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKKKKKAQE 540
  541 QGVAFSRSPE ELQAMWSALA ERLLQCAQEP ELSVDSIIPF DAASEVPVEE QRVEAMVRIQ 600
  601 DCLVAGQAPQ ALALLRSARE VWPEGNVFGS PVISPGEEMQ LLKQILSATL PRQQEPVEGD 660
  661 AEEEDEEEEE EEEEELQVVQ VSEKEFKFLD YLKRFACSTI VRAYVLLLRS YRQNSAHTNH 720
  721 CIAKMLHRLA HDLGMEALLF QLSLFCLFNQ LLSDPAAAAY KELVTFAKYI LGKFFALAAV 780
  781 NQKAFVELLF WKNTSVVREM TQGYGSLDSG SCSHRAPVWS SEEEAQLQEL YLAHKDVEGQ 840
  841 DVVETILAHL KAVPRTRKQV IHHLVRMGLA DSVKDFQRKG TQIVLWTEDQ ELELQRLFEE 900
  901 FQDSDDVLGH IMKNITAKRS RARVVDKLLA LGLVSERRQL HKKRRKKLAP SCMQNGEESQ 960
  961 RDAWQEDPEE EEEKEGLPES EGEENEEDLL AGQVQGSSSL SAENLRQSLC QDGLSAPLLW1020
 1021 LQSSLIRAAD DREEDGCSQA IPLVPLTEEN EEAMENKQFQ HLLRKLGIRA PCSGQETFWR1080
 1081 IPAKLSSTQL RRVAASLSER ENKEEREEEP EPNPGVPGEQ SPSEEHQVRA PRALLSARKR1140
 1141 KAGLVFPKEE ATGEEEWKSV PKKQQLLDSD EEDTDDERGG QAAVSGTLRI HKEKRFLVED1200
 1201 EDEDY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Protein Overview: TIM_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: