Protein Overview: ERBB4_RAT

General Information:
Name(s) found:	ERBB4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|4176735\|gb\|AAD08899.1\| receptor tyrosine kinase [Rattus norvegicus] [NCBI NR] gi\|21431759\|sp\|Q62956.3\|ERBB4_RAT RecName: Full=Receptor tyrosine-protein kinase erbB-4; Flags: Precursor [NCBI NR] gi\|11067415\|ref\|NP_067719.1\| v-erb-a erythroblastic leukemia viral oncogene homolog 4 [Rattus norvegicus] [NCBI NR] Receptor tyrosine-protein kinase erbB-4 OS=Rattus norvegicus GN=Erbb4 PE=1 SV=3 [Swiss-Prot] (Q62956) Receptor protein-tyrosine kinase erbB-4 precursor (EC 2.7.1.112) [Swiss-Prot] Ensembl_locations(Chr-bp):9-72553350 Receptor protein-tyrosine kinase erbB-4 precursor [hmr_yeast5_DM3-1_pombe.fasta] receptor tyrosine kinase [HMR_022704-rand.fasta] v-erb-a erythroblastic leukemia viral oncogene homolog 4 [Rattus norvegicus]gi\|4176735\|gb\|AAD08899.1\| receptor tyrosine kinase [Rattus norvegicus]gi\|21431759\|sp\|Q62956\|ERB4_RAT Receptor protein-tyrosine kinase erbB-4 precursor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Receptor tyrosine-protein kinase erbB-4 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_021687) receptor tyrosine kinase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Receptor tyrosine-protein kinase erbB-4 precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] v-erb-a erythroblastic leukemia viral oncogene homolog 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] receptor tyrosine kinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 RECEPTOR PROTEIN-TYROSINE KINASE ERBB-4 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Erbb4 Isoform 1 of Receptor tyrosine-protein kinase erbB-4 [rat-ipi-250309-contam.fasta] receptor tyrosine-protein kinase erbB-4 precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform JM-A CYT1 of Receptor tyrosine-protein kinase erbB-4 OS=Rattus norvegicus GN=Erbb4 [011711_HMR.fasta] Receptor tyrosine-protein kinase erbB-4 OS=Rattus norvegicus GN=Erbb4 PE=2 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1308 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] postsynaptic density [IDA] caveola [IDA] cytoplasm [IDA] membrane [IEA] membrane raft [IDA] integral to membrane [IEA] basolateral plasma membrane [UNKNOWN][IEA] plasma membrane [IDA][TAS]
Biological Process:	peptidyl-tyrosine phosphorylation [IEA] telencephalon development [IEP] positive regulation of synaptic transmission, GABAergic [IMP] signal transduction [UNKNOWN][IEA] synapse maturation [IMP] response to progesterone stimulus [IEP] nervous system development [UNKNOWN] transmembrane receptor protein tyrosine kinase signaling pathway [IEA][TAS] positive regulation of glucose import [IMP] odontogenesis [IEP][NAS] response to hydrogen peroxide [IEP] regulation of transcription [IEA] positive regulation of anti-apoptosis [IMP] surfactant homeostasis [IMP] heart development [UNKNOWN][IEA] mammary gland development [IEP] response to drug [IEP] cell fate commitment [UNKNOWN][IEA] positive regulation of epithelial cell proliferation [IMP] positive regulation of cell migration [IMP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [UNKNOWN][IDA][IEA][TAS] transmembrane receptor protein tyrosine kinase activity [IEA] receptor signaling protein tyrosine kinase activity [IEA] receptor activity [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLATGLWVW GSLLVAARTV QPSASQSVCA GTENKLSSLS DLEQQYRALR KYYENCEVVM  60
   61 GNLEITSIEH NRDLSFLRSI REVTGYVLVA LNQFRYLPLE NLRIIRGTKL YEDRYALAIF 120
  121 LNYRKDGNFG LQELGLKNLT EILNGGVYVD QNKFLCYADT IHWQDIVRNP WPSNMTLVST 180
  181 IGSSGCGRCH KSCTGRCWGP TENHCQTLTR TVCAEQCDGR CYGPYVSDCC HRECAGGCSG 240
  241 PKDTDCFACM NFNDSGACVT QCPQTFVYNP TTFQLEHNFN AKYTYGAFCV KKCPHNFVVD 300
  301 SSSCVRACPS SKMEVEENGI KMCKPCTDIC PKACDGIGTG SLMSAQTVDS SNIDKFINCT 360
  361 KINGNLIFLV TGIHGDPYNA IDAIDPEKLN VFRTVREITG FLNIQTWPPN MTDFSVFSNL 420
  421 VTIGGRVLYS GLSLLILKQQ GITSLQFQSL KEISAGNIYI TDNSNLCYYH TINWTTLFST 480
  481 VNQRIVIRDN RRAENCTAEG MVCNHLCSND GCWGPGPDQC LSCRRFSRGK ICIESCNLYD 540
  541 GEFREFENGS ICVECDSQCE KMEDGLLTCH GPGPDNCTKC SHFKDGPNCV EKCPDVLQGA 600
  601 NSFIFKYADQ DRECHPCHPN CTQGCNGPTS HDCIYYPWTG HSTLPQHART PLIAAGVIGG 660
  661 LFILVIMALT FAVYVRRKSI KKKRALRRFL ETELVEPLTP SGTAPNQAQL RILKETELKR 720
  721 VKVLGSGAFG TVYKGIWVPE GETVKIPVAI KILNETTGPK ANVEFMDEAL IMASVDHPHL 780
  781 VRLLGVCLSP TIQLVTQLMP HGCLLEYVHE HKDNIGSQLL LNWCVQIAKG MMYLEERRLV 840
  841 HRDLAARNVL VKSPNHVKIT DFGLARLLEG DEKEYNADGG KMPIKWMALE CIHYRKFTHQ 900
  901 SDVWSYGVTI WELMTFGGKP YDGIPTREIP DLLEKGERLP QPPICTIDVY IVMVKCWMID 960
  961 ADSRPKFKEL AAEFSRMARD PQRYLVIQGD DRMKLPSPND SKFFQNLLDE EDLEDMMDAE1020
 1021 EYLVPQAFNI PPPIYTSRTR IDSNRSEIGH SPPPAYTPMS GSQFVYQDGG FATQQGMPMP1080
 1081 YTATTSTIPE APVAQGATAE MFDDSCCNGT LRKPVVPHVQ EDSSTQRYSA DPTVFAPERN1140
 1141 PRAELDEEGY MTPMHDKPKQ EYLNPVEENP FVSRRKNGDL QALDNPEYHS ASSGPPKAED1200
 1201 EYVNEPLYLN TFTNALGNAE YMKNSLLSVP EKAKKAFDNP DYWNHSLPPR STLQHPDYLQ1260
 1261 EYSTKYFYKQ NGRIRPIVAE NPEYLSEFSL KPGTMLPPPP YRHRNTVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ERBB4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: