Protein Overview: COMT_RAT

General Information:
Name(s) found:	COMT_RAT [Swiss-Prot]
Description(s) found: Found 20 descriptions. SHOW ALL	Catechol O-methyltransferase OS=Rattus norvegicus GN=Comt PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	264 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] soluble fraction [IDA] cytoplasm [IEA] mitochondrion [UNKNOWN][IEA] integral to membrane [IEA] cytosol [UNKNOWN] plasma membrane [IEA]
Biological Process:	dopamine metabolic process [TAS] reproductive process in a multicellular organism [IMP] estrogen metabolic process [IMP] female pregnancy [IMP] negative regulation of dopamine metabolic process [IMP] dopamine catabolic process [UNKNOWN][IEA] catecholamine metabolic process [TAS] response to organic cyclic substance [IEP] neurotransmitter catabolic process [IEA] S-adenosylmethionine metabolic process [TAS] learning [IMP] response to pain [IMP] S-adenosylhomocysteine metabolic process [TAS] response to drug [IEP] negative regulation of smooth muscle cell proliferation [IMP] response to lipopolysaccharide [IEP] positive regulation of homocysteine metabolic process [IMP]
Molecular Function:	magnesium ion binding [TAS] catechol O-methyltransferase activity [UNKNOWN][IDA] protein binding [UNKNOWN][IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLAAVSLGL LLLALLLLLR HLGWGLVTIF WFEYVLQPVH NLIMGDTKEQ RILRYVQQNA  60
   61 KPGDPQSVLE AIDTYCTQKE WAMNVGDAKG QIMDAVIREY SPSLVLELGA YCGYSAVRMA 120
  121 RLLQPGARLL TMEMNPDYAA ITQQMLNFAG LQDKVTILNG ASQDLIPQLK KKYDVDTLDM 180
  181 VFLDHWKDRY LPDTLLLEKC GLLRKGTVLL ADNVIVPGTP DFLAYVRGSS SFECTHYSSY 240
  241 LEYMKVVDGL EKAIYQGPSS PDKS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: COMT_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: