Protein Overview: MK12_RAT

General Information:
Name(s) found:	MK12_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|3023701\|sp\|Q63538.1\|MK12_RAT RecName: Full=Mitogen-activated protein kinase 12; AltName: Full=Extracellular signal-regulated kinase 6; Short=ERK-6; AltName: Full=Stress-activated protein kinase 3; AltName: Full=Mitogen-activated protein kinase p38 gamm [NCBI NR] pir\|\|S68680 stress-activated protein kinase (EC 2.7.1.-) 3 - rat [NCBI NR] gi\|1588683\|prf\|\|2209285A SAP kinase 3 [NCBI NR] gi\|149017541\|gb\|EDL76545.1\| mitogen-activated protein kinase 12, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|1262403\|emb\|CAA65342.1\| SAP kinase-3 [Rattus norvegicus] [NCBI NR] gi\|11120692\|ref\|NP_068514.1\| mitogen-activated protein kinase 12 [Rattus norvegicus] [NCBI NR] Mitogen-activated protein kinase 12 OS=Rattus norvegicus GN=Mapk12 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):7-117443702;7-117443702 Mitogen-activated protein kinase 12 [hmr_yeast5_DM3-1_pombe.fasta] SAP kinase-3 [HMR_022704-rand.fasta] SAP kinase-3 [Rattus norvegicus]gi\|1262403\|emb\|CAA65342.1\| SAP kinase-3 [Rattus norvegicus]gi\|2143985\|pir\|\|S68680 stress-activated protein kinase (EC 2.7.1.-) 3 - ratgi\|3023701\|sp\|Q63538\|MK12_RAT Mitogen-activated protein kinase 12 (Extracellular signa [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Mitogen-activated protein kinase 12 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_021746) SAP kinase-3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Mitogen-activated protein kinase 12 (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitogen-activated protein kinase 12 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitogen-activated protein kinase 12, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SAP kinase-3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SAP kinase 3 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 MITOGEN-ACTIVATED PROTEIN KINASE 12 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Mapk12 Mitogen-activated protein kinase 12 [rat-ipi-250309-contam.fasta] Mitogen-activated protein kinase 12 OS=Rattus norvegicus GN=Mapk12 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	367 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA]
Biological Process:	myoblast differentiation [UNKNOWN] Ras protein signal transduction [UNKNOWN] protein amino acid phosphorylation [IDA]
Molecular Function:	magnesium ion binding [UNKNOWN] ATP binding [IDA] protein binding [UNKNOWN] MAP kinase activity [IDA] protein serine/threonine kinase activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPPPARKG FYRQEVTKTA WEVRAVYQDL QPVGSGAYGA VCSAVDSRTG NKVAIKKLYR  60
   61 PFQSELFAKR AYRELRLLKH MRHENVIGLL DVFTPDETLD DFTDFYLVMP FMGTDLGKLM 120
  121 KHETLSEDRI QFLVYQMLKG LKYIHAAGVI HRDLKPGNLA VNEDCELKIL DFGLARQADS 180
  181 EMTGYVVTRW YRAPEVILNW MRYTQTVDIW SVGCIMAEMI TGKILFKGND HLDQLKEIMK 240
  241 VTGTPPPEFV QKLQSAEAKN YMEGLPELEK KDFASVLTNA SPQAVNLLEK MLVLDAEQRV 300
  301 TAAEALAHPY FESLRDTEDE PKAQKYDDSF DDVDRTLEEW KRVTYKEVLS FKPPRQLGAR 360
  361 VPKETAL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: MK12_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: