Protein Overview: ROCK2_RAT, ROC2_RAT

General Information:
Name(s) found:	ROCK2_RAT [Swiss-Prot] ROC2_RAT [Swiss-Prot]
Description(s) found: Found 16 descriptions. SHOW ALL	Rho-associated protein kinase 2 OS=Rattus norvegicus GN=Rock2 PE=1 SV=1 [Swiss-Prot] (Q62868) Rho-associated protein kinase 2 (EC 2.7.1.37) (Rho-associated, coiled-coil containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1379 amino acids
Gene Ontology:
Cellular Component:	spindle pole centrosome [UNKNOWN] centrosome [UNKNOWN] cytoplasm [IEA] cytosol [UNKNOWN] intracellular [IEA] plasma membrane [IEA]
Biological Process:	signal transduction [IEA] positive regulation of centrosome duplication [UNKNOWN] chromosome condensation [TAS] cytokinesis [IEA] Rho protein signal transduction [IMP] protein amino acid phosphorylation [IEA] actin cytoskeleton organization [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [UNKNOWN][IEA] metal ion binding [IEA] protein serine/threonine kinase activity [IEA] transferase activity [IEA] kinase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGAPEAAAG DGAGAGRQRK LEALIRDPRS PINVESLLDG LNSLVLDLDF PALRKNKNID  60
   61 NFLNRYEKIV KKIRGLQMKA EDYDVVKVIG RGAFGEVQLV RHKASQKVYA MKLLSKFEMI 120
  121 KRSDSAFFWE ERDIMAFANS PWVVQLFCAF QDDRYLYMVM EYMPGGDLVN LMSNYDVPEK 180
  181 WAKFYTAEVV LALDAIHSMG LIHRDVKPDN MLLDKHGHLK LADFGTCMKM DETGMVHCDT 240
  241 AVGTPDYISP EVLKSQGGDG YYGRECDWWS VGVFLFEMLV GDTPFYADSL VGTYSKIMDH 300
  301 KNSLCFPEDT EISKHAKNLI CAFLTDREVR LGRNGVEEIK SASFFKNDQW NWDNIRETAA 360
  361 PVVPELSSDI DSSNFDDIED DKGDVETFPI PKAFVGNQLP FIGFTYFREN LLLSDSPPCR 420
  421 ENDAIQTRKS EESQEIQKKL YALEEHLSSE VQAKEELEQK CKSINTRLEK TAKELEEEIT 480
  481 FRKNVESTLR QLEREKALLQ HKNAEYQRKA DHEADKKRNL ENDVNSLKDQ LEDLKKRNQS 540
  541 SQISTEKVNQ LQKQLDEANA LLRTESDTAA RLRKTQAESS KQIQQLESNN RDLQDKNCLL 600
  601 ETAKLKLEKE FINLQSALES ERRDRTHGSE IINDLQGRIS GLEEDLKTGK TLLAKVELEK 660
  661 RQLQEKLTDL EKEKSNMEID MTYQLKVIQQ SLEQEEAEHK TTKARLADKN KIYESIEEAK 720
  721 SEAMKEMEKK LLEERSLKQK VENLLLEAEK RCSILDCDLK QSQQKLNELL KQKDVLNEDV 780
  781 RNLTLKIEQE TQKRCLMQND LKMQTQQVNT LKMSEKQIKQ ENNHLMEMKM NLEKQNAELR 840
  841 KERQDADGQM KELQDQLEAE QYFSTLYKTQ VRELKEENEE KTKLCKELQQ KKQDLQDERD 900
  901 SLAAQLEITL TKADSEQLAR SIAEEQYSDL EKEKIMKELE IKEMMARHKQ ELTEKDATIA 960
  961 SLEETNRTLT SDVANLANEK EELNNKLKDT QEQLSKLKDE EISAAAIKAQ FEKQLLTERT1020
 1021 LKTQAVNKLA EIMNRKEPVK RGSDTDVRRK EKENRKLHME LKSEREKLTQ QMIKYQKELN1080
 1081 EMQAQIAEES QIRIELQMTL DSKDSDIEQL RSQLQALHIG MDSSSIGSGP GDAEPDDGFP1140
 1141 ESRLEGWLSL PVRNNTKKFG WVKKYVIVSS KKILFYDSEQ DKEQSNPYMV LDIDKLFHVR1200
 1201 PVTQTDVYRA DAKEIPRIFQ ILYANEGESK KEPEFPVEPV GEKSNYICHK GHEFIPTLYH1260
 1261 FPTNCEACMK PLWHMFKPPP ALECSRCHIK CHKDHMDKKE EIIAPCKVYY DISSAKNLLL1320
 1321 LANSTEEQQK WVSRLVKKIP KKPPAPDPFA RSSPRTSMKI QQNQSIRRPS RQLAPNKPS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ROCK2_RAT, ROC2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: