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Protein Overview: FGF12_RAT

General Information:
Name(s) found: FGF12_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Fibroblast growth factor 12 OS=Rattus norvegicus GN=Fgf12 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 243 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    Biological Process: cell-cell signaling [IPI]
    [NOT]fibroblast growth factor receptor signaling pathway [UNKNOWN]
    JNK cascade [UNKNOWN][IEA]
    Molecular Function: growth factor activity [TAS]
    protein binding [IPI]
    heparin binding [UNKNOWN][IEA]
    [NOT]fibroblast growth factor receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAIASSLI RQKRQARESN SDRVSASKRR SSPSKDGRSL CERHVLGVFS KVRFCSGRKR  60
   61 PVRRRPEPQL KGIVTRLFSQ QGYFLQMHPD GTIDGTKDEN SDYTLFNLIP VGLRVVAIQG 120
  121 VKASLYVAMN GEGYLYSSDV FTPECKFKES VFENYYVIYS STLYRQQESG RAWFLGLNKE 180
  181 GQIMKGNRVK KTKPSSHFVP KPIEVCMYRE PSLHEIGEKQ GRSRKSSGTP TMNGGKVVNQ 240
  241 DST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..243] PSI-BLAST 50.69897 Crystal structure of human FHF1b (FGF12b)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  4.30358117760805 bayes_pls_golite062009
  • growth factor activity
    		•  3.97089267530575 bayes_pls_golite062009
  • cytokine activity
    		•  3.76931834545338 bayes_pls_golite062009
  • binding
    		•  2.90110516688922 bayes_pls_golite062009
  • protein binding
    		•  1.94397222237906 bayes_pls_golite062009
  • fibroblast growth factor receptor binding
    		•  1.9437092554389 bayes_pls_golite062009
  • pattern binding
    		•  0.839280621598109 bayes_pls_golite062009
  • interleukin-1 receptor binding
    		•  0.8084616632765 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.69866345905635 bayes_pls_golite062009
  • heparin binding
    		•  0.290941670257021 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle