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Protein Overview: TFF1_RAT

General Information:
Name(s) found: TFF1_RAT [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Trefoil factor 1 OS=Rattus norvegicus GN=Tff1 PE=3 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 81 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    cytoplasm [TAS]
    extracellular region [IEA]
    Biological Process: wound healing [TAS]
    negative regulation of cell proliferation [UNKNOWN]
    response to iron ion [IEP]
    cell differentiation [UNKNOWN]
    response to estradiol stimulus [UNKNOWN][IEA]
    maintenance of gastrointestinal epithelium [IEP]
    response to peptide hormone stimulus [IEP]
    response to stress [IEP]
    Molecular Function: growth factor activity [IEA]
    protein binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHKVTCVLA MVLMLALSSL AQNQEETCAV IPRERINCGF PGVTAQQCKE KGCCFDDSVR  60
   61 GFPWCFRPLV IENQQEEECP F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..81] PSI-BLAST 13.69897 SOLUTION STRUCTURE OF A TREFOIL-MOTIF-CONTAINING CELL GROWTH FACTOR, PORCINE SPASMOLYTIC PROTEIN

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.30259381288946 bayes_pls_golite062009
  • protein binding
    		•  0.524855475418758 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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