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Protein Overview: PDE1C_RAT

General Information:
Name(s) found: PDE1C_RAT [Swiss-Prot]
Description(s) found:
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  • gi|871805|gb|AAB00868.1| cyclic nucleotide phosphodiesterase [NCBI NR]
  • pir||T10796 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) - rat [NCBI NR]
  • gi|2499447|sp|Q63421.1|PDE1C_RAT RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Short=Cam-PDE 1C [NCBI NR]
  • gi|23618922|ref|NP_112340.1| phosphodiesterase 1C [Rattus norvegicus] [NCBI NR]
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C OS=Rattus norvegicus GN=Pde1c PE=1 SV=1 [Swiss-Prot]
  • (Q63421) Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):4-89227193 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [hmr_yeast5_DM3-1_pombe.fasta]
  • cyclic nucleotide phosphodiesterase 1 C; phosphodiesterase 1C calmodulin-dependent (70kD) [HMR_022704-rand.fasta]
  • cyclic nucleotide phosphodiesterase 1 C [Rattus norvegicus]gi|2499447|sp|Q63421|CN1C_RAT Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C)gi|7513900|pir||T10796 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • phosphodiesterase 1C [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • cyclic nucleotide phosphodiesterase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • cyclic nucleotide phosphodiesterase 1 C [Rattus norvegicus] [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Pde1c Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C [rat-ipi-250309-contam.fasta]
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C OS=Rattus norvegicus GN=Pde1c [011711_HMR.fasta]
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C OS=Rattus norvegicus GN=Pde1c PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 768 amino acids

    Gene Ontology:
    Cellular Component: cytosol [UNKNOWN]
    neuronal cell body [IDA]
    Biological Process: signal transduction [IEA]
    cGMP catabolic process [IDA]
    sensory perception of smell [IEP]
    cAMP catabolic process [IDA]
    negative regulation of insulin secretion [IMP]
    Molecular Function: calmodulin-dependent cyclic-nucleotide phosphodiesterase activity [IDA]
    catalytic activity [IEA]
    calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity [IDA]
    cAMP binding [IDA]
    3',5'-cyclic-AMP phosphodiesterase activity [IDA]
    3',5'-cyclic-nucleotide phosphodiesterase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDTSHKKEG FKKCRSATFS IDGYSFTIVA NEAGDKNARP LARFSRSKSQ NCLWNSLIDG  60
   61 LTGNVKEKPR PTIVQDTRPP EEILADELPQ LDSPEALVKT SFRLRSLVKQ LERGEASVVD 120
  121 LKKNLEYAAT VLESVYIDET RRLLDTEDEL SDIQSDAVPS EVRDWLASTF TRQMGMMLRR 180
  181 SDEKPRFKSI VHAVQAGIFV ERMYRRTSNM VGLSYPPAVI DALKDVDTWS FDVFSLNEAS 240
  241 GDHALKFIFY ELLTRYDLIS RFKIPISALV SFVEALEVGY SKHKNPYHNL MHAADVTQTV 300
  301 HYLLYKTGVA NWLTELEIFA IIFSAAIHDY EHTGTTNNFH IQTRSDPAIL YNDRSVLENH 360
  361 HLSAAYRLLQ EDEEMNILVN LSKDDWREFR TLVIEMVMAT DMSCHFQQIK AMKTALQQPE 420
  421 AIEKPKALSL MLHTADISHP AKAWDLHHRW TMSLLEEFFR QGDREAELGL PFSPLCDRKS 480
  481 TMVAQSQVGF IDFIVEPTFT VLTDMTEKIV SPLIDETSQT GGTGQRRSSL NSINSSDAKR 540
  541 SGVKSSGSEG SAPINNSVIP VDYKSFKATW TEVVQINRER WRAKVPKEEK AKKEAEEKAR 600
  601 LAAEEKQKEM EAKSQAEQGT TSKAEKKTSG ETKGQVNGTR TSKGDNPRGK NSKGDKAGEK 660
  661 QQNGDLKDGK NKADKKDHSN TGNESKKADG TKKRSHGSPA PSTSSTSRLT LPVIKPPLRH 720
  721 FKRPAYASSS YAPSVPKKTD DHPVRYKMLD QRIKIKKIQN ISHHWNKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle