Protein Overview: CSF1_RAT

General Information:
Name(s) found:	CSF1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|28201782\|sp\|Q8JZQ0.1\|CSF1_RAT RecName: Full=Macrophage colony-stimulating factor 1; Short=CSF-1; Short=MCSF; Contains: RecName: Full=Processed macrophage colony-stimulating factor 1; Flags: Precursor [NCBI NR] gi\|22255878\|gb\|AAM94802.1\|AF515736_1 colony stimulating factor-1 [Rattus norvegicus] [NCBI NR] gi\|21449443\|gb\|AAM54136.1\|AF514356_1 macrophage colony stimulating factor [Rattus norvegicus] [NCBI NR] gi\|21449440\|gb\|AAM54135.1\|AF514355_1 macrophage colony stimulating factor [Rattus norvegicus] [NCBI NR] gi\|149025646\|gb\|EDL81889.1\| colony stimulating factor 1 (macrophage), isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|149025644\|gb\|EDL81887.1\| colony stimulating factor 1 (macrophage), isoform CRA_b [Rattus norvegicus] [NCBI NR] Macrophage colony-stimulating factor 1 OS=Rattus norvegicus GN=Csf1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-198024585 Macrophage colony stimulating factor-1 precursor [hmr_yeast5_DM3-1_pombe.fasta] colony stimulating factor 1 (macrophage) [HMR_022704-rand.fasta] colony stimulating factor-1 [Rattus norvegicus]gi\|21449443\|gb\|AAM54136.1\| macrophage colony stimulating factor [Rattus norvegicus]gi\|21449440\|gb\|AAM54135.1\| macrophage colony stimulating factor [Rattus norvegicus]gi\|28201782\|sp\|Q8JZQ0\|CSF1_RAT Macropha [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Macrophage colony-stimulating factor 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_023981) colony stimulating factor 1(macrophage) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Macrophage colony stimulating factor-1 precursor [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) [Contains: Processed macrophage colony-stimulating factor 1] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] colony stimulating factor 1 (macrophage), isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] colony stimulating factor-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] macrophage colony stimulating factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 MACROPHAGE COLONY STIMULATING FACTOR-1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Csf1 Macrophage colony-stimulating factor 1 [rat-ipi-250309-contam.fasta] Isoform 1 of Macrophage colony-stimulating factor 1 OS=Rattus norvegicus GN=Csf1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	566 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [TAS] extracellular space [UNKNOWN][IEA] perinuclear region of cytoplasm [UNKNOWN][IEA] receptor complex [IEA] extracellular region [IEA] plasma membrane [IEA]
Biological Process:	positive regulation of cellular protein metabolic process [UNKNOWN][IEA] multicellular organismal development [TAS] positive regulation of cell proliferation [UNKNOWN][IEA] positive regulation of Ras protein signal transduction [UNKNOWN][IEA] odontogenesis [IMP] branching involved in mammary gland duct morphogenesis [UNKNOWN][IEA] mammary duct terminal end bud growth [UNKNOWN][IEA] positive regulation of multicellular organism growth [UNKNOWN][IEA] positive regulation of mononuclear cell proliferation [UNKNOWN][IEA] reproductive developmental process [IEA] positive regulation of osteoclast differentiation [UNKNOWN][IEA] ossification [IMP] positive regulation of macrophage differentiation [UNKNOWN][IEA] macrophage differentiation [IEP] positive regulation of odontogenesis of dentine-containing tooth [UNKNOWN][IEA] mammary gland fat development [UNKNOWN][IEA] positive regulation of monocyte differentiation [UNKNOWN][IEA] osteoclast differentiation [IMP][TAS] positive regulation of cell-matrix adhesion [UNKNOWN][IEA] positive regulation of protein kinase activity [UNKNOWN][IEA] homeostasis of number of cells within a tissue [UNKNOWN][IEA] positive regulation of gene expression [UNKNOWN][IEA] positive regulation of macrophage derived foam cell differentiation [UNKNOWN][IEA] regulation of ossification [UNKNOWN][IEA] positive regulation of cell migration [UNKNOWN][IEA]
Molecular Function:	growth factor activity [UNKNOWN][IEA] protein binding [IEA] protein homodimerization activity [UNKNOWN][IDA] cytokine activity [UNKNOWN][IEA] macrophage colony stimulating factor receptor binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTARGAAGRC PSSTWMGSRL LLVCLLVSRS VAEVSEHCSH MIGNGHLQIL QQLIDSQMET  60
   61 ACLIEYKFVD QEQLDDPVCY LKKAFVLVQV IIEETMRFKD NTPNANATER LQELSMKLNS 120
  121 CFIKDYKEQN EACVQTYKES PLRLLEKIKN FFNETKNFLE KDWNIFSKNC NDSFAKCSSR 180
  181 DVVTKPDCNC LYPKATPSSD LASASPHQPP APSMAPLADL AWDDSQRTEG SSLLPSDLPL 240
  241 RIEDPGSAKQ RPPRSTCQTL ESTEQPNHED PQPHPSAGAP IPGVEDIIES SMGTNWVLEE 300
  301 ASGEASEGFL TQERKFSPSN PVGGSIQAET DRPWARSASS PFPKLTEDQQ PTNITDTPLT 360
  361 EVNPMRPTGQ TLNNTPEKTD GSSTLREDQQ EPRSPHFATL NPQRVGNSAT PYAKLLPPKS 420
  421 HSWGIVLPLG ELEGKKSTRD RRSPAELKGG PASEGAARPV AQSTRDRRSP AELKGGPASE 480
  481 GAARPVARFN SIPLTDTGSS IQDPQTSAFV FWVLGIILVL LAVGGLLFYS WKRRSHRDPR 540
  541 TLDSSVGRPE GSSLAQDEDR QVELPV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CSF1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: