Protein Overview: PLOD1_RAT

General Information:
Name(s) found:	PLOD1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6093729\|sp\|Q63321.1\|PLOD1_RAT RecName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; AltName: Full=Lysyl hydroxylase 1; Short=LH1; Flags: Precursor [NCBI NR] gi\|409059\|gb\|AAA41550.1\| lysyl hydroxylase [NCBI NR] pir\|\|S59964 procollagen-lysine 5-dioxygenase (EC 1.14.11.4) precursor - rat [NCBI NR] gi\|16758678\|ref\|NP_446279.1\| lysyl hydroxylase 1 [Rattus norvegicus] [NCBI NR] gi\|1584463\|prf\|\|2123247A Lys hydroxylase [NCBI NR] Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Rattus norvegicus GN=Plod1 PE=2 SV=1 [Swiss-Prot] (Q63321) Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1) [Swiss-Prot] Ensembl_locations(Chr-bp):5-185824632;5-185824632 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor [hmr_yeast5_DM3-1_pombe.fasta] procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) [HMR_022704-rand.fasta] procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) [Rattus norvegicus]gi\|6093729\|sp\|Q63321\|PLO1_RAT Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor (Lysyl hydroxylase 1) (LH1)gi\|2143937\|pir\| [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053827) procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor (Lysyl hydroxylase 1) (LH1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Lys hydroxylase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] lysyl hydroxylase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Plod1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [rat-ipi-250309-contam.fasta] Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Rattus norvegicus GN=Plod1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	728 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] rough endoplasmic reticulum membrane [IEA] membrane [IEA] endoplasmic reticulum [IEA]
Biological Process:	response to hypoxia [UNKNOWN][IEP] peptidyl-lysine hydroxylation [IDA] epidermis development [UNKNOWN] cellular response to hormone stimulus [IEP] oxidation reduction [IEA]
Molecular Function:	L-ascorbic acid binding [IMP] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] ferrous iron binding [IMP] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEA] metal ion binding [IEA] peptide binding [IDA][IMP] procollagen-lysine 5-dioxygenase activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSLLLLASL AWLLLAQAKD DAKLEDNLLV LTVATKETEG FRRFKRSAQF FNYKIQSLGL  60
   61 GEDWSAAGGP SAAGGGQKVR LLKKALKKYA DKEDLVILFV DSYDVVFASG PRELLKKFQQ 120
  121 AKSRVVFSAE ELIYPDRRLE AKYPTVPDGK RFLGSGGFIG YAPSLSKLVA EWEGQDNDSD 180
  181 QLFYTKIFLD PEKREQINIS LDHRCRIFQN LDGALDEVVL KFEMGHVRAR NLAYDTLPVV 240
  241 IHGNGPTKLQ VNYLGNYIPR FWTFETGCTV CDEGLRSLKG IGDEALPTVL VGVFIEQPTP 300
  301 FLSLFFRRLL HLRYPQKQMR LFIHNQEQHH KLQVEQFLAE HGGEYQSVKL VGPEVRMANA 360
  361 DARNMGADLC RQDQTCTYYF SVDADVALTE PNSLRLLIEQ NKNVIAPLMT RHGRLWSNFW 420
  421 GALSADGYYA RSEDYVDIVQ GRRVGVWNVP YISNIYLIKG SALRAELRHV DLFHYSKLDP 480
  481 DMSFCANVRQ QEVFMFLTNR HTFGHLLSLD NYQTTHLHND LWEVFSNPQD WKEKYIHENY 540
  541 TKALAGKLVE TPCPDVYWFP IFTEVACDEL VEEMEHYGQW SLGDNKDNRI QGGYENVPTI 600
  601 DIHMNQITFE REWHKFLVEY IAPLTEKLYP GYYTKAQFDL AFVVRYKPDE QPSLMPHHDA 660
  661 STFTINIALN RVGEDYEGGG CRFLRYNCSV RAPRKGWALM HPGRLTHYHE GLPTTKGTRY 720
  721 IAVSFVDP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PLOD1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: