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Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: procollagen-lysine 5-dioxygenase activity
Acc: GO:0008475
Aspect: Molecular Function
Desc: Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.
Synonyms:
  • lysylprotocollagen dioxygenase activity
  • procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)
  • protocollagen lysine dioxygenase activity
  • lysine hydroxylase activity
  • lysyl hydroxylase activity
  • protocollagen lysine hydroxylase activity
  • collagen lysine hydroxylase activity
  • procollagen-lysine,2-oxoglutarate 5-dioxygenase activity
  • protocollagen lysyl hydroxylase activity
  • lysine,2-oxoglutarate 5-dioxygenase activity
  • lysine-2-oxoglutarate dioxygenase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008475 - procollagen-lysine 5-dioxygenase activity (interactive image map)
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Created and Maintained by: Michael Riffle