Protein Overview: NK1R_RAT

General Information:
Name(s) found:	NK1R_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981628\|ref\|NP_036799.1\| tachykinin receptor 1 [Rattus norvegicus] [NCBI NR] gi\|62647614\|ref\|XP_579342.1\| PREDICTED: tachykinin receptor 1 [Rattus norvegicus] [NCBI NR] gi\|207059\|gb\|AAA42176.1\| substance P receptor [NCBI NR] gi\|207052\|gb\|AAA42175.1\| substance P receptor [NCBI NR] gi\|149036477\|gb\|EDL91095.1\| rCG56054, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149036476\|gb\|EDL91094.1\| rCG56054, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|128360\|sp\|P14600.1\|NK1R_RAT RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1 [NCBI NR] pir\|\|A34357 neurokinin 1 receptor - rat [NCBI NR] Substance-P receptor OS=Rattus norvegicus GN=Tacr1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-120166456 Substance-P receptor [hmr_yeast5_DM3-1_pombe.fasta] tachykinin receptor 1; Tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor); Tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor), see also D4Mgh17, D4Wox19 and D4Mit23; Tachykinin 1 receptor; substance p receptor; neurokinin [HMR_022704-rand.fasta] tachykinin receptor 1; Tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor); Tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor), see also D4Mgh17, D4Wox19 and D4Mit23; substance p receptor; neurokinin 1 receptor; Tachykinin [071204_hmrz_cont.fasta] tachykinin receptor 1 [Rattus norvegicus]gi\|112335\|pir\|\|A34357 neurokinin 1 receptor - ratgi\|128360\|sp\|P14600\|NK1R_RAT Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)gi\|207059\|gb\|AAA42176.1\| substance P receptorgi\|207052\|gb\| [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Substance-P receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012667) tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor); tachykinin receptor 1; Tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor), see also D4Mgh17, D4Wox19 and D4Mit23 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] tachykinin receptor 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG56054, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] substance P receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SUBSTANCE-P RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tacr1 Substance-P receptor [rat-ipi-250309-contam.fasta] Substance-P receptor OS=Rattus norvegicus GN=Tacr1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	407 amino acids
Gene Ontology:
Cellular Component:	dendrite [IDA] cytoplasm [IDA] integral to membrane [IEA] plasma membrane [UNKNOWN][IEA] cell surface [IDA]
Biological Process:	sperm ejaculation [IMP] positive regulation of synaptic transmission, GABAergic [IMP] positive regulation of vasoconstriction [IMP] associative learning [IMP] positive regulation of natriuresis [IMP] tachykinin receptor signaling pathway [UNKNOWN][IEA] eating behavior [IMP] response to pain [UNKNOWN] response to ethanol [IMP] response to heat [IMP] aggressive behavior [IMP] positive regulation of lymphocyte proliferation [IMP] behavioral response to pain [IMP] response to auditory stimulus [IDA] positive regulation of synaptic transmission, cholinergic [IMP] positive regulation of epithelial cell migration [IMP] positive regulation of epithelial cell proliferation [IMP] signal transduction [IEA] response to ozone [IMP] response to organic cyclic substance [IDA] response to nicotine [IMP] response to morphine [IEP] response to hormone stimulus [IMP] regulation of blood pressure [IMP] response to stress [IEP] positive regulation of blood pressure [IMP] elevation of cytosolic calcium ion concentration [IMP] positive regulation of ossification [IMP] long-term memory [IMP] neuropeptide signaling pathway [TAS] positive regulation of action potential [IMP] positive regulation of uterine smooth muscle contraction [IDA] acute inflammatory response [IEP] positive regulation of stress fiber assembly [IMP] sensory perception of pain [IMP][TAS] smooth muscle contraction involved in micturition [IMP] operant conditioning [IMP]
Molecular Function:	G-protein coupled receptor activity [IEA] protein binding [UNKNOWN][IEA] substance P receptor activity [IDA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNVLPMDSD LFPNISTNTS ESNQFVQPTW QIVLWAAAYT VIVVTSVVGN VVVIWIILAH  60
   61 KRMRTVTNYF LVNLAFAEAC MAAFNTVVNF TYAVHNVWYY GLFYCKFHNF FPIAALFASI 120
  121 YSMTAVAFDR YMAIIHPLQP RLSATATKVV IFVIWVLALL LAFPQGYYST TETMPSRVVC 180
  181 MIEWPEHPNR TYEKAYHICV TVLIYFLPLL VIGYAYTVVG ITLWASEIPG DSSDRYHEQV 240
  241 SAKRKVVKMM IVVVCTFAIC WLPFHVFFLL PYINPDLYLK KFIQQVYLAS MWLAMSSTMY 300
  301 NPIIYCCLND RFRLGFKHAF RCCPFISAGD YEGLEMKSTR YLQTQSSVYK VSRLETTIST 360
  361 VVGAHEEEPE EGPKATPSSL DLTSNGSSRS NSKTMTESSS FYSNMLA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NK1R_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: