Protein Overview: DLG1_RAT

General Information:
Name(s) found:	DLG1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978763\|ref\|NP_036920.1\| discs large homolog 1 [Rattus norvegicus] [NCBI NR] gi\|642456\|gb\|AAA79976.1\| synapse-associated protein 97 [NCBI NR] gi\|2497505\|sp\|Q62696.1\|DLG1_RAT RecName: Full=Disks large homolog 1; AltName: Full=Synapse-associated protein 97; Short=SAP-97 [NCBI NR] pir\|\|I56552 synapse-associated protein 97 - rat [NCBI NR] Disks large homolog 1 OS=Rattus norvegicus GN=Dlg1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):11-17639809 Presynaptic protein SAP97 [hmr_yeast5_DM3-1_pombe.fasta] discs large homolog 1; Drosophila discs-large tumor suppressor homologue (synapse associated protein) [HMR_022704-rand.fasta] discs large homolog 1 [Rattus norvegicus]gi\|2143987\|pir\|\|I56552 synapse-associated protein 97 - ratgi\|642456\|gb\|AAA79976.1\| synapse-associated protein 97gi\|2497505\|sp\|Q62696\|DLG1_RAT Presynaptic protein SAP97 (Synapse-associated protein 97) (Discs, lar [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Disks large homolog 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Presynaptic protein SAP97 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_012788) drosophila discs-large tumor suppressor homologue (synapse associated protein) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] discs large homolog 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] synapse-associated protein 97 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PRESYNAPTIC PROTEIN SAP97 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Dlg1 Disks large homolog 1 [rat-ipi-250309-contam.fasta] Disks large homolog 1 OS=Rattus norvegicus GN=Dlg1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	911 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [IDA] postsynaptic density [UNKNOWN][IDA][TAS] lateral plasma membrane [UNKNOWN] synaptosome [IDA] endoplasmic reticulum [IEA] synapse [UNKNOWN][IEA] plasma membrane [UNKNOWN][IDA] immunological synapse [UNKNOWN] endoplasmic reticulum membrane [IEA] T-tubule [IDA] basal plasma membrane [IDA] postsynaptic membrane [TAS] membrane raft [UNKNOWN] cytosol [UNKNOWN] cell junction [UNKNOWN][IEA] cell projection membrane [UNKNOWN] neuromuscular junction [UNKNOWN] basolateral plasma membrane [UNKNOWN][ISS]
Biological Process:	hard palate development [UNKNOWN] positive regulation of cell proliferation [UNKNOWN] protein localization [UNKNOWN] T cell activation [UNKNOWN] actin filament organization [UNKNOWN][ISS] cell adhesion [IEP] positive regulation of potassium ion transport [IMP] lens development in camera-type eye [UNKNOWN] formation of immunological synapse [UNKNOWN] cortical actin cytoskeleton organization [UNKNOWN][ISS] activation of protein kinase activity [UNKNOWN] membrane raft organization [UNKNOWN] cell-cell adhesion [UNKNOWN][ISS] reproductive structure development [UNKNOWN] tissue morphogenesis [UNKNOWN] regulation of protein localization [IMP] negative regulation of mitotic cell cycle [UNKNOWN][ISS] smooth muscle tissue development [UNKNOWN] amyloid precursor protein metabolic process [UNKNOWN] embryonic skeletal system morphogenesis [UNKNOWN] T cell cytokine production [UNKNOWN] regulation of membrane potential [UNKNOWN] ureteric bud development [UNKNOWN] branching involved in ureteric bud morphogenesis [UNKNOWN] negative regulation of T cell proliferation [UNKNOWN] positive regulation of actin filament polymerization [UNKNOWN] negative regulation of epithelial cell proliferation [UNKNOWN] endothelial cell proliferation [UNKNOWN][ISS] peristalsis [UNKNOWN]
Molecular Function:	phosphatase binding [UNKNOWN][ISS] protein kinase binding [UNKNOWN][ISS] protein complex scaffold [UNKNOWN] ionotropic glutamate receptor binding [IPI] protein binding [UNKNOWN][IEA][IPI] protein C-terminus binding [UNKNOWN][IPI] PDZ domain binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVRKQDTQR ALHLLEEYRS KLSQTEDRQL RSSIERVISI FQSNLFQALI DIQEFYEVTL  60
   61 LDNPKCVDHS KQCEPVQPGN PWESGSLSSA AVTSESLPGG LSPPVEKYRY QDEEVLPSER 120
  121 ISPQVPNEVL GPELVHVSEK SLSEIENVHG FVSHSHISPI KPTEAVPPSS PIVPVTPALP 180
  181 VPAESPVVLP STPQANPPPV LVNTDSLETP TYVNGTDADY EYEEITLERG NSGLGFSIAG 240
  241 GTDNPHIGDD SSIFITKIIT GGAAAQDGRL RVNDCILRVN EADVRDVTHS KAVEALKEAG 300
  301 SIVRLYVKRR KAFRKNHEIK LIKGPKGLGF SIAGGVGNQH IPGDNSIYVT KIIEGGAAHK 360
  361 DGKLQIGDKL LAVNSVCLEE VTHEEAVTAL KNTSDFVYLK AAKPTSMYIN DGYAPPDITN 420
  421 SSSQSVDNHV SPSSYLGQTP ASPARYSPIS KAVLGDDEIT REPRKVVLHR GSTGLGFNIV 480
  481 GGEDGEGIFI SFILAGGPAD LSGELRKGDR IISVNSVDLR AASHEQAAAA LKNAGQAVTI 540
  541 VAQYRPEEYS RFEAKIHDLR ETMMNSSVSS GSGSLRTSQK RSLYVRALFD YDKTKDSGLP 600
  601 SQGLNFKFGD ILHVINASDD EWWQARQVTP DGESDEVGVI PSKRRVEKKE RARLKTVKFN 660
  661 SKTRGDKGEI PDDMGSKGLK HVTSNASDSE SSYHEYGCSK GGQEEYVLSY EPVNQQEVNY 720
  721 TRPVIILGPM KDRVNDDLIS EFPDKFGSCV PHTTRPKRDY EVDGRDYHFV TSREQMEKDI 780
  781 QEHKFIEAGQ YNNHLYGTSV QSVRAVAEKG KHCILDVSGN AIKRLQIAQL YPISIFIKPK 840
  841 SMENIMEMNK RLTDEQARKT FERAVRLEQE FTEHFTAIVQ GDTLEDIYNQ VKQIIEEQSG 900
  901 PYIWVPAKEK L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: DLG1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: