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Protein Overview: DLG1_RAT

General Information:
Name(s) found: DLG1_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Disks large homolog 1 OS=Rattus norvegicus GN=Dlg1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 911 amino acids

    Gene Ontology:
    Cellular Component: presynaptic membrane [IDA]
    postsynaptic density [UNKNOWN][IDA][TAS]
    lateral plasma membrane [UNKNOWN]
    synaptosome [IDA]
    endoplasmic reticulum [IEA]
    synapse [UNKNOWN][IEA]
    plasma membrane [UNKNOWN][IDA]
    immunological synapse [UNKNOWN]
    endoplasmic reticulum membrane [IEA]
    T-tubule [IDA]
    basal plasma membrane [IDA]
    postsynaptic membrane [TAS]
    membrane raft [UNKNOWN]
    cytosol [UNKNOWN]
    cell junction [UNKNOWN][IEA]
    cell projection membrane [UNKNOWN]
    neuromuscular junction [UNKNOWN]
    basolateral plasma membrane [UNKNOWN][ISS]
    Biological Process: hard palate development [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN]
    protein localization [UNKNOWN]
    T cell activation [UNKNOWN]
    actin filament organization [UNKNOWN][ISS]
    cell adhesion [IEP]
    positive regulation of potassium ion transport [IMP]
    lens development in camera-type eye [UNKNOWN]
    formation of immunological synapse [UNKNOWN]
    cortical actin cytoskeleton organization [UNKNOWN][ISS]
    activation of protein kinase activity [UNKNOWN]
    membrane raft organization [UNKNOWN]
    cell-cell adhesion [UNKNOWN][ISS]
    reproductive structure development [UNKNOWN]
    tissue morphogenesis [UNKNOWN]
    regulation of protein localization [IMP]
    negative regulation of mitotic cell cycle [UNKNOWN][ISS]
    smooth muscle tissue development [UNKNOWN]
    amyloid precursor protein metabolic process [UNKNOWN]
    embryonic skeletal system morphogenesis [UNKNOWN]
    T cell cytokine production [UNKNOWN]
    regulation of membrane potential [UNKNOWN]
    ureteric bud development [UNKNOWN]
    branching involved in ureteric bud morphogenesis [UNKNOWN]
    negative regulation of T cell proliferation [UNKNOWN]
    positive regulation of actin filament polymerization [UNKNOWN]
    negative regulation of epithelial cell proliferation [UNKNOWN]
    endothelial cell proliferation [UNKNOWN][ISS]
    peristalsis [UNKNOWN]
    Molecular Function: phosphatase binding [UNKNOWN][ISS]
    protein kinase binding [UNKNOWN][ISS]
    protein complex scaffold [UNKNOWN]
    ionotropic glutamate receptor binding [IPI]
    protein binding [UNKNOWN][IEA][IPI]
    protein C-terminus binding [UNKNOWN][IPI]
    PDZ domain binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVRKQDTQR ALHLLEEYRS KLSQTEDRQL RSSIERVISI FQSNLFQALI DIQEFYEVTL  60
   61 LDNPKCVDHS KQCEPVQPGN PWESGSLSSA AVTSESLPGG LSPPVEKYRY QDEEVLPSER 120
  121 ISPQVPNEVL GPELVHVSEK SLSEIENVHG FVSHSHISPI KPTEAVPPSS PIVPVTPALP 180
  181 VPAESPVVLP STPQANPPPV LVNTDSLETP TYVNGTDADY EYEEITLERG NSGLGFSIAG 240
  241 GTDNPHIGDD SSIFITKIIT GGAAAQDGRL RVNDCILRVN EADVRDVTHS KAVEALKEAG 300
  301 SIVRLYVKRR KAFRKNHEIK LIKGPKGLGF SIAGGVGNQH IPGDNSIYVT KIIEGGAAHK 360
  361 DGKLQIGDKL LAVNSVCLEE VTHEEAVTAL KNTSDFVYLK AAKPTSMYIN DGYAPPDITN 420
  421 SSSQSVDNHV SPSSYLGQTP ASPARYSPIS KAVLGDDEIT REPRKVVLHR GSTGLGFNIV 480
  481 GGEDGEGIFI SFILAGGPAD LSGELRKGDR IISVNSVDLR AASHEQAAAA LKNAGQAVTI 540
  541 VAQYRPEEYS RFEAKIHDLR ETMMNSSVSS GSGSLRTSQK RSLYVRALFD YDKTKDSGLP 600
  601 SQGLNFKFGD ILHVINASDD EWWQARQVTP DGESDEVGVI PSKRRVEKKE RARLKTVKFN 660
  661 SKTRGDKGEI PDDMGSKGLK HVTSNASDSE SSYHEYGCSK GGQEEYVLSY EPVNQQEVNY 720
  721 TRPVIILGPM KDRVNDDLIS EFPDKFGSCV PHTTRPKRDY EVDGRDYHFV TSREQMEKDI 780
  781 QEHKFIEAGQ YNNHLYGTSV QSVRAVAEKG KHCILDVSGN AIKRLQIAQL YPISIFIKPK 840
  841 SMENIMEMNK RLTDEQARKT FERAVRLEQE FTEHFTAIVQ GDTLEDIYNQ VKQIIEEQSG 900
  901 PYIWVPAKEK L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle