Protein Overview: PARP1_RAT

General Information:
Name(s) found:	PARP1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978455\|ref\|NP_037195.1\| poly (ADP-ribose) polymerase family, member 1 [Rattus norvegicus] [NCBI NR] gi\|55250408\|gb\|AAH85765.1\| Poly (ADP-ribose) polymerase 1 [Rattus norvegicus] [NCBI NR] gi\|3123251\|sp\|P27008.4\|PARP1_RAT RecName: Full=Poly [ADP-ribose] polymerase 1; Short=PARP-1; AltName: Full=ADPRT; AltName: Full=NAD(+) ADP-ribosyltransferase 1; AltName: Full=Poly[ADP-ribose] synthetase 1 [NCBI NR] gi\|2896792\|gb\|AAC53544.1\| poly(ADP-ribose) polymerase [Rattus norvegicus] [NCBI NR] gi\|149040870\|gb\|EDL94827.1\| poly (ADP-ribose) polymerase family, member 1 [Rattus norvegicus] [NCBI NR] Poly [ADP-ribose] polymerase 1 OS=Rattus norvegicus GN=Parp1 PE=1 SV=4 [Swiss-Prot] Ensembl_locations(Chr-bp):13-89134509 ADP-ribosyltransferase 1 [hmr_yeast5_DM3-1_pombe.fasta] ADP-ribosyltransferase 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); poly(ADP-ribose) polymerase PARP-1 [HMR_022704-rand.fasta] ADP-ribosyltransferase 1 [Rattus norvegicus]gi\|6978455\|ref\|NP_037195.1\| ADP-ribosyltransferase 1 [Rattus norvegicus]gi\|2896792\|gb\|AAC53544.1\| poly(ADP-ribose) polymerase [Rattus norvegicus]gi\|3123251\|sp\|P27008\|PPOL_RAT Poly [ADP-ribose] polymerase-1 (P [nrdb_11152004_Chlamydomonas] (NM_013063) ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Poly [ADP-ribose] polymerase 1 (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ADP-ribosyltransferase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] poly (ADP-ribose) polymerase family, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Poly (ADP-ribose) polymerase family, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] poly(ADP-ribose) polymerase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ADP-RIBOSYLTRANSFERASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Parp1 Poly [ADP-ribose] polymerase 1 [rat-ipi-250309-contam.fasta] Poly [ADP-ribose] polymerase 1 OS=Rattus norvegicus GN=Parp1 [011711_HMR.fasta] ADP-ribosyltransferase 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); poly(ADP-ribose) polymerase PARP-1 [Rattus norvegicus] [H3-CATD_Contrast.fasta] Poly [ADP-ribose] polymerase 1 OS=Rattus norvegicus GN=Parp1 PE=2 SV=4 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1014 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN][IEA] nucleus [IDA][NAS] transcription factor complex [UNKNOWN][IEA] nucleolus [UNKNOWN][IEA] intracellular [IEA] nucleoplasm [UNKNOWN][IEA]
Biological Process:	cellular response to insulin stimulus [UNKNOWN][IEA] DNA damage response, detection of DNA damage [IDA] base-excision repair [UNKNOWN][IEA] protein amino acid ADP-ribosylation [UNKNOWN][IDA] telomere maintenance [UNKNOWN][IEA] protein autoprocessing [IDA] DNA metabolic process [UNKNOWN] regulation of growth rate [UNKNOWN][IEA] regulation of transcription [IEA]
Molecular Function:	DNA binding [IEA] zinc ion binding [IEA] identical protein binding [UNKNOWN][IEA] protein binding [UNKNOWN] metal ion binding [IEA] NAD or NADH binding [IDA] protein N-terminus binding [UNKNOWN][IEA] transcription factor binding [UNKNOWN][IEA] transferase activity, transferring pentosyl groups [NAS] NAD+ ADP-ribosyltransferase activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEATERLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV  60
   61 GHSIRQPDTE VDGFSELRWD DQQKVKKTAE AGGVAGKGQH GGGGKAEKTL GDFAAEYAKS 120
  121 NRSTCKGCME KIEKGQMRLS KKMLDPEKPQ LGMIDRWYHP TCFVKNRDEL GFRPEYSASQ 180
  181 LKGFSLLSAE DKEALKKQLP AVKSEGKRKC DEVDGIDEVA KKKSKKGKDK ESSKLEKALK 240
  241 AQNELVWNIK DELKKACSTN DLKELLIFNQ QQVPSGESAI LDRVADGMAF GALLPCKECS 300
  301 GQLVFKSDAY YCTGDVTAWT KCMVKTQNPS RKEWVTPKEF REISYLKKLK IKKQDRLFPP 360
  361 ESSAPAPPAP PVSITSAPTA VNSSAPADKP LSNMKILTLG KLSQNKDEAK AMIEKLGGKL 420
  421 TGSANKASLC ISTKKEVEKM SKKMEEVKAA NVRVVCEDFL QDVSASAKSL QELLSAHSLS 480
  481 SWGAEVKVEP GEVVVPKGKS AAPSKKSKGA VKEEGVNKSE KRMKLTLKGG AAVDPDSGLE 540
  541 HSAHVLEKGG KVFSATLGLV DIVKGTNSYY KLQLLESDKE SRYWIFRSWG RVGTVIGSNK 600
  601 LEQMPSKEDA VEHFMKLYEE KTGNAWHSKN FTKYPKKFYP LEIDYGQDEE AVKKLAVKPG 660
  661 TKSKLPKPVQ ELVGMIFDVE SMKKALVEYE IDLQKMPLGK LSRRQIQAAY SILSEVQQAV 720
  721 SQGSSESQIL DLSNRFYTLI PHDFGMKKPP LLNNTDSVQA KVEMLDNLLD IEVAYSLLRG 780
  781 GSDDSSKDPI DVNYEKLKTD IKVVDRDSEE AEVIRKYVKN THATTHNAYD LEVIDIFKIE 840
  841 REGESQRYKP FRQLHNRRLL WHGSRTTNFA GILSQGLRIA PPEAPVTGYM FGKGIYFADM 900
  901 VSKSANYCHT SQGDPIGLIL LGEVALGNMY ELKHASHISK LPKGKHSVKG LGKTAPDPSA 960
  961 SITLDGVEVP LGTGIPSGVN DTCLLYNEYI VYDIAQVNLK YLLKLKFNFK TSLW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PARP1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: