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Protein Overview: NR1I2_RAT

General Information:
Name(s) found: NR1I2_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Nuclear receptor subfamily 1 group I member 2 OS=Rattus norvegicus GN=Nr1i2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 431 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: drug export [UNKNOWN][ISS]
    exogenous drug catabolic process [UNKNOWN][ISS]
    negative regulation of transcription [UNKNOWN][IEA]
    xenobiotic metabolic process [UNKNOWN][ISS]
    regulation of transcription, DNA-dependent [IEA]
    xenobiotic transport [UNKNOWN][ISS]
    positive regulation of transcription [UNKNOWN][ISS]
    Molecular Function: transcription factor activity [IEA]
    zinc ion binding [IEA]
    protein binding [UNKNOWN][IEA]
    drug binding [UNKNOWN][ISS]
    ligand-dependent nuclear receptor activity [UNKNOWN][IDA][ISS]
    metal ion binding [IEA]
    steroid hormone receptor activity [IEA]
    sequence-specific DNA binding [IEA]
    transcription repressor activity [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPEERWNHV GLVQREEADS VLEEPINVDE EDGGLQICRV CGDKANGYHF NVMTCEGCKG  60
   61 FFRRAMKRNV RLRCPFRKGT CEITRKTRRQ CQACRLRKCL ESGMKKEMIM SDAAVEQRRA 120
  121 LIKRKKREKI EAPPPGGQGL TEEQQALIQE LMDAQMQTFD TTFSHFKDFR LPAVFHSDCE 180
  181 LPEVLQASLL EDPATWSQIM KDSVPMKISV QLRGEDGSIW NYQPPSKSDG KEIIPLLPHL 240
  241 ADVSTYMFKG VINFAKVISH FRELPIEDQI SLLKGATFEM CILRFNTMFD TETGTWECGR 300
  301 LAYCFEDPNG GFQKLLLDPL MKFHCMLKKL QLREEEYVLM QAISLFSPDR PGVVQRSVVD 360
  361 QLQERFALTL KAYIECSRPY PAHRFLFLKI MAVLTELRSI NAQQTQQLLR IQDTHPFATP 420
  421 LMQELFSSTD G

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle