Protein Overview: PO3F3_RAT

General Information:
Name(s) found:	PO3F3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5915802\|sp\|Q63262.2\|PO3F3_RAT RecName: Full=POU domain, class 3, transcription factor 3; AltName: Full=Brain-specific homeobox/POU domain protein 1; Short=Brain-1; Short=Brn-1 protein [NCBI NR] gi\|2760445\|emb\|CAA04893.1\| Brain-1 (Brn-1) protein [Rattus norvegicus] [NCBI NR] gi\|20301970\|ref\|NP_620192.1\| POU class 3 homeobox 3 [Rattus norvegicus] [NCBI NR] POU domain, class 3, transcription factor 3 OS=Rattus norvegicus GN=Pou3f3 PE=1 SV=2 [Swiss-Prot] (Q63262) POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein) [Swiss-Prot] Ensembl_locations(Chr-bp):None POU domain, class 3, transcription factor 3 [hmr_yeast5_DM3-1_pombe.fasta] POU domain, class 3, transcription factor 3 [HMR_022704-rand.fasta] POU domain, class 3, transcription factor 3 [Rattus norvegicus]gi\|2760445\|emb\|CAA04893.1\| Brain-1 (Brn-1) protein [Rattus norvegicus]gi\|5915802\|sp\|Q63262\|PO33_RAT POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 POU domain, class 3, transcription factor 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_138837) POU domain, class 3, transcription factor 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] POU domain, class 3, transcription factor 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Brain-1 (Brn-1) protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] POU class 3 homeobox 3 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pou3f3 POU domain, class 3, transcription factor 3 [rat-ipi-250309-contam.fasta] POU domain, class 3, transcription factor 3 OS=Rattus norvegicus GN=Pou3f3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	497 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][IMP]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [IGI] kidney development [UNKNOWN][IEA] multicellular organismal development [IEA] positive regulation of gene expression [IMP][ISS] negative regulation of transcription [ISS] forebrain ventricular zone progenitor cell division [UNKNOWN][IEA] negative regulation of apoptosis [ISS] nervous system development [NAS] regulation of transcription, DNA-dependent [IEA] cerebral cortex radially oriented cell migration [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
Molecular Function:	DNA binding [UNKNOWN] protein binding [IEA] RNA polymerase II transcription factor activity, enhancer binding [IDA] sequence-specific DNA binding [ISS] transcription activator activity [IDA][IMP] transcription repressor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATAASNPYL PGNSLLAAGS IVHSDAAGAG GGGGGGGGGG GGAGGGGGGM QPGSAAVTSG  60
   61 AYRGDPSSVK MVQSDFMQGA MAASNGGHML SHAHQWVTAL PHAAAAAAAA AAAAVEASSP 120
  121 WSGSAVGMAG SPQQPPRPPP PPPQGPDVKG GVGREDLHAG TALHHRGPPH LGPPPPPPHQ 180
  181 GHPGGWGAAA AAAAAAAAAA AAAHLPSMAG GQQPPPQSLL YSQPGGFTVN GMLSAPPGPG 240
  241 GGGGGAGGGA QSLVHPGLVR GDTPELAEHH HHHHHHAHPH PPHPHHAQGP PHHGGGGAGP 300
  301 GLNSHDPHSD EDTPTSDDLE QFAKQFKQRR IKLGFTQADV GLALGTLYGN VFSQTTICRF 360
  361 EALQLSFKNM CKLKPLLNKW LEEADSSTGS PTSIDKIAAQ GRKRKKRTSI EVSVKGALES 420
  421 HFLKCPKPSA QEITNLADSL QLEKEVVRVW FCNRRQKEKR MTPPGIQQQT PDDVYSQVGT 480
  481 VSADTPPPHH GLQTSVQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PO3F3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: