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Protein Overview: CDN2A_RAT

General Information:
Name(s) found: CDN2A_RAT [Swiss-Prot]
Description(s) found:
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  • gi|77416385|sp|Q9R0Z3.1|CD2A1_RAT RecName: Full=Cyclin-dependent kinase inhibitor 2A, isoform 1; AltName: Full=Cyclin-dependent kinase 4 inhibitor A; Short=CDK4I; AltName: Full=p16-INK4a; Short=p16-INK4; Short=p16 [NCBI NR]
  • gi|5732022|gb|AAD48924.1| p16 protein P16INK4a [Rattus norvegicus] [NCBI NR]
  • gi|51012355|gb|AAT92510.1| cyclin-dependent kinase inhibitor 2a p16Ink4a [Rattus norvegicus] [NCBI NR]
  • gi|18644706|gb|AAL76339.1|AF474977_1 cyclin-dependent kinase inhibitor 2a p16Ink4a [Rattus norvegicus] [NCBI NR]
  • gi|18644704|gb|AAL76338.1|AF474976_1 cyclin-dependent kinase inhibitor 2a p16Ink4a [Rattus norvegicus] [NCBI NR]
  • gi|149044485|gb|EDL97744.1| rCG53482, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|13928746|ref|NP_113738.1| cyclin dependent kinase inhibitor 2A [Rattus norvegicus] [NCBI NR]
  • Cyclin-dependent kinase inhibitor 2A OS=Rattus norvegicus GN=Cdkn2a PE=2 SV=1 [Swiss-Prot]
  • Cyclin-dependent kinase inhibitor 2A, isoform 1 OS=Rattus norvegicus GN=Cdkn2a PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):5-126720515 P16 protein P16INK4a [hmr_yeast5_DM3-1_pombe.fasta]
  • cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); Cyclin dependent kinase inhibitor 2A (p16 inhibits CDK4) [HMR_022704-rand.fasta]
  • cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); Cyclin dependent kinase inhibitor 2A (p16 inhibits CDK4); cell cycle inhibitor; cyclin-dependent kinase inhibitor 2a p16Ink4a [071204_hmrz_cont.fasta]
  • cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4) [Rattus norvegicus]gi|51012355|gb|AAT92510.1| cyclin-dependent kinase inhibitor 2a p16Ink4a [Rattus norvegicus]gi|18644706|gb|AAL76339.1| cyclin-dependent kinase inhibitor 2a p16Ink4a [Rattus nor [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Cyclin-dependent kinase inhibitor 2A, isoform 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_031550) cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Tax_Id=10116 P16 protein P16INK4a [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta]
  • cyclin dependent kinase inhibitor 2A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Cyclin-dependent kinase inhibitor 2A, isoform 1 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4a) (p16-INK4) (p16) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG53482, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • cyclin-dependent kinase inhibitor 2a p16Ink4a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • p16 protein P16INK4a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 P16 PROTEIN P16INK4A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Cyclin-dependent kinase inhibitor 2A, isoform 1 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16) [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Cdkn2a Cyclin-dependent kinase inhibitor 2A, isoform 1 [rat-ipi-250309-contam.fasta]
  • Isoform 1 of Cyclin-dependent kinase inhibitor 2A, isoform 1 OS=Rattus norvegicus GN=Cdkn2a [011711_HMR.fasta]
  • Isoform of Q8QZZ9, Cyclin-dependent kinase inhibitor 2A OS=Rattus norvegicus GN=Cdkn2a PE=2 SV=1 [RAT.fasta.20160308]
    • Organism: Rattus norvegicus
    Length: 159 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    cytoplasm [IEA]
    nucleolus [IEA]
    Biological Process: response to organic substance [IEP]
    response to drug [IDA][IEP]
    apoptosis [IEA]
    negative regulation of cell cycle [TAS]
    rRNA processing [IEA]
    response to organic cyclic substance [IDA]
    aging [IEP]
    regulation of transcription [IEA]
    response to organic nitrogen [IDA]
    Molecular Function: DNA binding [IEA]
    cyclin-dependent protein kinase inhibitor activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESSADRLAR AAALGREHEV RALLEAGASP NAPNTFGRTP IQVMMMGNVK VAALLLSYGA  60
   61 DSNCEDPTTL SRPVHDAARE GFLDTLVVLH QAGARLDVRD AWGRLPLDLA LERGHHDVVR 120
  121 YLRYLLSSAG NVSRVTDRHN FCSSTPRCLG LRGQPPKQR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle