Protein Overview: TIMP1_RAT

General Information:
Name(s) found:	TIMP1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|71681153\|gb\|AAH99821.1\| TIMP metallopeptidase inhibitor 1 [Rattus norvegicus] [NCBI NR] gi\|468058\|gb\|AAA85780.1\| tissue inhibitor of metalloproteinase-1 [NCBI NR] gi\|45239052\|gb\|AAS55641.1\| tissue inhibitor of metalloproteinase 1 [Rattus norvegicus] [NCBI NR] gi\|16758666\|ref\|NP_446271.1\| TIMP metallopeptidase inhibitor 1 [Rattus norvegicus] [NCBI NR] gi\|149044405\|gb\|EDL97726.1\| tissue inhibitor of metalloproteinase 1 [Rattus norvegicus] [NCBI NR] gi\|1174697\|sp\|P30120.2\|TIMP1_RAT RecName: Full=Metalloproteinase inhibitor 1; AltName: Full=TIMP-1; Flags: Precursor [NCBI NR] gi\|1161234\|gb\|AAA85373.1\| matrix metalloproteinase inhibitor [NCBI NR] pir\|\|JC2557 metalloproteinase inhibitor 1 precursor - rat [NCBI NR] Metalloproteinase inhibitor 1 OS=Rattus norvegicus GN=Timp1 PE=1 SV=2 [Swiss-Prot] (P30120) Metalloproteinase inhibitor 1 precursor (TIMP-1) [Swiss-Prot] Ensembl_locations(Chr-bp):6-129702192 Metalloproteinase inhibitor 1 precursor [hmr_yeast5_DM3-1_pombe.fasta] tissue inhibitor of metalloproteinase 1 [HMR_022704-rand.fasta] tissue inhibitor of metalloproteinase 1 [Rattus norvegicus]gi\|1174697\|sp\|P30120\|TIM1_RAT Metalloproteinase inhibitor 1 precursor (TIMP-1)gi\|1085572\|pir\|\|JC2557 metalloproteinase inhibitor 1 precursor - ratgi\|45239052\|gb\|AAS55641.1\| tissue inhibitor of [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Metalloproteinase inhibitor 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053819) tissue inhibitor of metalloproteinase 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Metalloproteinase inhibitor 1 precursor (TIMP-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tissue inhibitor of metalloproteinase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tissue inhibitor of metalloproteinase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tissue inhibitor of metalloproteinase-1 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] matrix metalloproteinase inhibitor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 METALLOPROTEINASE INHIBITOR 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] TIMP metallopeptidase inhibitor 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tissue inhibitor of metallopeptidase 1 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Timp1 Metalloproteinase inhibitor 1 [rat-ipi-250309-contam.fasta] Metalloproteinase inhibitor 1 OS=Rattus norvegicus GN=Timp1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	217 amino acids
Gene Ontology:
Cellular Component:	basement membrane [UNKNOWN][IEA] extracellular matrix [IDA] extracellular region [IEA] proteinaceous extracellular matrix [UNKNOWN]
Biological Process:	response to cytokine stimulus [IEP] cell activation [IMP] response to organic substance [IEP] wound healing [IEP] negative regulation of membrane protein ectodomain proteolysis [UNKNOWN] negative regulation of apoptosis [IMP] steroid biosynthetic process [IEA] aging [IEP] response to peptide hormone stimulus [IEP] erythrocyte maturation [IEA] cartilage development [IEP]
Molecular Function:	protein binding [UNKNOWN][IEA] enzyme inhibitor activity [IEA] metal ion binding [IEA] metalloendopeptidase inhibitor activity [UNKNOWN][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPFASLASG ILLLLSLIAS SKACSCAPTH PQTAFCNSDL VIRAKFMGSP EIIETTLYQR  60
   61 YEIKMTKMLK GFDAVGNATG FRFAYTPAME SLCGYVHKSQ NRSEEFLIAG RLRNGNLHIT 120
  121 ACSFLVPWHN LSPAQQKAFV KTYSAGCGVC TVFPCSAIPC KLESDSHCLW TDQILMGSEK 180
  181 GYQSDHFACL PRNPDLCTWQ YLGVSMTRSL PLAKAEA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TIMP1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: