Protein Overview: HMGCL_RAT

General Information:
Name(s) found:	HMGCL_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|38511566\|gb\|AAH61797.1\| 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase [Rattus norvegicus] [NCBI NR] gi\|2495261\|sp\|P97519.1\|HMGCL_RAT RecName: Full=Hydroxymethylglutaryl-CoA lyase, mitochondrial; Short=HMG-CoA lyase; Short=HL; AltName: Full=3-hydroxy-3-methylglutarate-CoA lyase; Flags: Precursor [NCBI NR] gi\|1743378\|emb\|CAA71148.1\| 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus] [NCBI NR] gi\|149024282\|gb\|EDL80779.1\| 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13242293\|ref\|NP_077362.1\| 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus] [NCBI NR] (P97519) Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (EC 4.1.3.4) (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase) [Swiss-Prot] Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus norvegicus GN=Hmgcl PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):5-175166878;5-175166878 Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] 3-hydroxy-3-methylglutaryl CoA lyase [HMR_022704-rand.fasta] 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus]gi\|38511566\|gb\|AAH61797.1\| 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus]gi\|1743378\|emb\|CAA71148.1\| 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus]gi\|2495261\|sp\|P97519\|HMGL_RAT [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_024386) 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-hydroxy-3-methylglutaryl-Coenzyme A lyase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 3-hydroxy-3-methylglutaryl CoA lyase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hmgcl Hydroxymethylglutaryl-CoA lyase, mitochondrial [rat-ipi-250309-contam.fasta] Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus norvegicus GN=Hmgcl [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	325 amino acids
Gene Ontology:
Cellular Component:	mitochondrial matrix [UNKNOWN][IEA] mitochondrion [UNKNOWN][IDA] mitochondrial inner membrane [UNKNOWN][IEA]
Biological Process:	acyl-CoA metabolic process [IDA] metabolic process [IEA] ketone body biosynthetic process [IDA]
Molecular Function:	carboxylic acid binding [IPI] acyl-CoA binding [IPI] metal ion binding [UNKNOWN][ISS] hydroxymethylglutaryl-CoA lyase activity [UNKNOWN][IDA][ISS] lyase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATVRKAFPQ RLVGLASLRA ASTSSMGTLP KRVKIVEVGP RDGLQNEKSI VPTPVKIKLI  60
   61 DMLSEAGLPV IEATSFVSPK WVPQMADHSD VLKGIQKFPG INYPVLTPNM KGFEEAVAAG 120
  121 AKEVSIFGAA SELFTRKNVN CSIEESFQRF DGVMQAARAA SISVRGYVSC ALGCPYEGKV 180
  181 SPAKVAEVAK KLYSMGCYEI SLGDTIGVGT PGLMKDMLTA VLHEVPVAAL AVHCHDTYGQ 240
  241 ALANTLVALQ MGVSVVDSSV AGLGGCPYAK GASGNLATED LVYMLTGLGI HTGVNLQKLL 300
  301 EAGDFICQAL NRKTSSKVAQ ATCKL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HMGCL_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: