Protein Overview: T23O_RAT

General Information:
Name(s) found:	T23O_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|59809151\|gb\|AAH89802.1\| Tryptophan 2,3-dioxygenase [Rattus norvegicus] [NCBI NR] gi\|207147\|gb\|AAA63503.1\| tryptophan-2,3-dioxygenase [NCBI NR] gi\|149048277\|gb\|EDM00853.1\| tryptophan 2,3-dioxygenase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|135212\|sp\|P21643.1\|T23O_RAT RecName: Full=Tryptophan 2,3-dioxygenase; Short=TDO; AltName: Full=Tryptophan pyrrolase; Short=Tryptophanase; AltName: Full=Tryptophan oxygenase; Short=TRPO; Short=TO; AltName: Full=Tryptamin 2,3-dioxygenase [NCBI NR] gi\|11693136\|ref\|NP_071798.1\| tryptophan 2,3-dioxygenase [Rattus norvegicus] [NCBI NR] pir\|\|A35484 tryptophan 2,3-dioxygenase (EC 1.13.11.11) - rat [NCBI NR] Tryptophan 2,3-dioxygenase OS=Rattus norvegicus GN=Tdo2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-168883798;2-168883798 Tryptophan 2,3-dioxygenase [hmr_yeast5_DM3-1_pombe.fasta] tryptophan 2,3-dioxygenase; tryptophan-2,3-dioxygenase; tryptophan-23-dioxygenase [HMR_022704-rand.fasta] tryptophan 2,3-dioxygenase; tryptophan-23-dioxygenase; tryptophan-2,3-dioxygenase [071204_hmrz_cont.fasta] tryptophan 2,3-dioxygenase [Rattus norvegicus]gi\|112453\|pir\|\|A35484 tryptophan 2,3-dioxygenase (EC 1.13.11.11) - ratgi\|207147\|gb\|AAA63503.1\| tryptophan-2,3-dioxygenasegi\|135212\|sp\|P21643\|T23O_RAT Tryptophan 2,3-dioxygenase (Tryptophan pyrrolase) (Trypt [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tryptophan 2,3-dioxygenase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022403) tryptophan 2,3-dioxygenase; tryptophan-2,3-dioxygenase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] tryptophan 2,3-dioxygenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tryptophan 2,3-dioxygenase (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tryptophan 2,3-dioxygenase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tryptophan 2,3-dioxygenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tryptophan-2,3-dioxygenase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRYPTOPHAN 2,3-DIOXYGENASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tdo2 Tryptophan 2,3-dioxygenase [rat-ipi-250309-contam.fasta] Tryptophan 2,3-dioxygenase OS=Rattus norvegicus GN=Tdo2 [011711_HMR.fasta] Tryptophan 2,3-dioxygenase OS=Rattus norvegicus GN=Tdo2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	406 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] cytosol [UNKNOWN]
Biological Process:	tryptophan catabolic process to kynurenine [IEA] tryptophan catabolic process to acetyl-CoA [IDA] oxidation reduction [IEA] tryptophan metabolic process [IDA]
Molecular Function:	oxygen binding [IDA] tryptophan 2,3-dioxygenase activity [UNKNOWN][IDA] oxidoreductase activity [IEA] metal ion binding [IEA] amino acid binding [IDA] heme binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGCPFSGNS VGYTLKNLSM EDNEEDGAQT GVNRASKGGL IYGDYLQLEK ILNAQELQSE  60
   61 IKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VMTRMHRVVV 120
  121 IFKLLVQQFS VLETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQS LRVPYNRKHY 180
  181 RDNFEGDYNE LLLKSEQEQT LLQLVEAWLE RTPGLEPHGF NFWGKFEKNI LKGLEEEFLK 240
  241 IQAKKDSEEK EEQMAEFRKQ KEVLLCLFDE KRHDYLLSKG ERRLSYRALQ GALMIYFYRE 300
  301 EPRFQVPFQL LTSLMDIDTL MTKWRYNHVC MVHRMLGSKA GTGGSSGYYY LRSTVSDRYK 360
  361 VFVDLFNLSS YLVPRHWIPK MNPIIHKFLY TAEYSDSSYF SSDESD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: T23O_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: