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The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate. The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents. The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan. The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan. The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). The chemical reactions and pathways involving compounds derived from indole (2,3-benzopyrrole). The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: tryptophan metabolic process
Acc: GO:0006568
Aspect: Biological Process
Desc: The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:
  • tryptophan metabolism
Proteins in PDR annotated with:
   This term: 30 [Search]
   Term or descendants: 178 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006568 - tryptophan metabolic process (interactive image map)

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