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Protein Overview: T23O_RAT

General Information:
Name(s) found: T23O_RAT [Swiss-Prot]
Description(s) found:
Found 22 descriptions.
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  • Tryptophan 2,3-dioxygenase OS=Rattus norvegicus GN=Tdo2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 406 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    cytosol [UNKNOWN]
    Biological Process: tryptophan catabolic process to kynurenine [IEA]
    tryptophan catabolic process to acetyl-CoA [IDA]
    oxidation reduction [IEA]
    tryptophan metabolic process [IDA]
    Molecular Function: oxygen binding [IDA]
    tryptophan 2,3-dioxygenase activity [UNKNOWN][IDA]
    oxidoreductase activity [IEA]
    metal ion binding [IEA]
    amino acid binding [IDA]
    heme binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGCPFSGNS VGYTLKNLSM EDNEEDGAQT GVNRASKGGL IYGDYLQLEK ILNAQELQSE  60
   61 IKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VMTRMHRVVV 120
  121 IFKLLVQQFS VLETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQS LRVPYNRKHY 180
  181 RDNFEGDYNE LLLKSEQEQT LLQLVEAWLE RTPGLEPHGF NFWGKFEKNI LKGLEEEFLK 240
  241 IQAKKDSEEK EEQMAEFRKQ KEVLLCLFDE KRHDYLLSKG ERRLSYRALQ GALMIYFYRE 300
  301 EPRFQVPFQL LTSLMDIDTL MTKWRYNHVC MVHRMLGSKA GTGGSSGYYY LRSTVSDRYK 360
  361 VFVDLFNLSS YLVPRHWIPK MNPIIHKFLY TAEYSDSSYF SSDESD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle