Protein Overview: PDK1_RAT

General Information:
Name(s) found:	PDK1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|438874\|gb\|AAA62851.1\| pyruvate dehydrogenase kinase kinase [NCBI NR] gi\|3183109\|sp\|Q63065.1\|PDK1_RAT RecName: Full=[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; AltName: Full=Pyruvate dehydrogenase kinase isoform 1; AltName: Full=PDK p48; Flags: Precursor [NCBI NR] ref\|NP_446278.1\| pyruvate dehydrogenase kinase 1 [Rattus norvegicus] [NCBI NR] pir\|\|A49686 [pyruvate dehydrogenase (lipoamide)] kinase (EC 2.7.1.99) precursor - rat [NCBI NR] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial OS=Rattus norvegicus GN=Pdk1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-166133909 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] pyruvate dehydrogenase kinase 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase isoenzyme 1 [HMR_022704-rand.fasta] pyruvate dehydrogenase kinase 1 [Rattus norvegicus]gi\|3183109\|sp\|Q63065\|PDK1_RAT [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (Pyruvate dehydrogenase kinase isoform 1) (PDK P48)gi\|1083830\|pir\|\|A49686 [pyruvate dehydroge [nrdb_11152004_Chlamydomonas] Tax_Id=10116 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053826) pyruvate dehydrogenase kinase 1; pyruvate dehydrogenase kinase, isoenzyme 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (Pyruvate dehydrogenase kinase isoform 1) (PDK p48) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] pyruvate dehydrogenase kinase kinase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 [PYRUVATE DEHYDROGENASE [LIPOAMIDE]] KINASE ISOZYME 1, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pdk1 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial [rat-ipi-250309-contam.fasta] [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial OS=Rattus norvegicus GN=Pdk1 [011711_HMR.fasta] [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial OS=Rattus norvegicus GN=Pdk1 PE=1 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	434 amino acids
Gene Ontology:
Cellular Component:	pyruvate dehydrogenase complex [IDA] mitochondrial matrix [IEA] mitochondrion [UNKNOWN][TAS]
Biological Process:	carbohydrate metabolic process [IEA] signal transduction [IEA] cell surface receptor linked signaling pathway [IMP] glucose metabolic process [IEA] protein amino acid phosphorylation [IDA] regulation of acetyl-CoA biosynthetic process from pyruvate [UNKNOWN] peptidyl-histidine phosphorylation [IEA]
Molecular Function:	two-component sensor activity [IEA] nucleotide binding [IEA] ATP binding [IDA] protein homodimerization activity [IDA] protein heterodimerization activity [IDA] protein kinase activity [UNKNOWN] pyruvate dehydrogenase (acetyl-transferring) kinase activity [IDA] transferase activity [IEA] protein complex binding [IDA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLARLLRGG TSVRPLCAVP CASRSLASDS ASGSGPASES GVPGQVDFYA RFSPSPLSMK  60
   61 QFLDFGSVNA CEKTSFMFLR QELPVRLANI MKEISLLPDN LLRTPSVQLV QSWYIQSLQE 120
  121 LLDFKDKSAE DAKTIYEFTD TVIRIRNRHN DVIPTMAQGV TEYKESFGVD PVTSQNVQYF 180
  181 LDRFYMSRIS IRMLLNQHSL LFGGKGSPSH RKHIGSINPN CDVVEVIKDG YENARRLCDL 240
  241 YYVNSPELEL EELNAKSPGQ PIQVVYVPSH LYHMVFELFK NAMRATMEHH ADKGVYPPIQ 300
  301 VHVTLGEEDL TVKMSDRGGG VPLRKIDRLF NYMYSTAPRP RVETSRAVPL AGFGYGLPIS 360
  361 RLYAQYFQGD LKLYSLEGYG TDAVIYIKAL STESIERLPV YNKAAWKHYR TNHEADDWCV 420
  421 PSREPKDMTT FRSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PDK1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: