Protein Overview: NOX1_RAT

General Information:
Name(s) found:	NOX1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8134593\|sp\|Q9WV87.1\|NOX1_RAT RecName: Full=NADPH oxidase 1; Short=NOX-1; AltName: Full=NOH-1; AltName: Full=NADH/NADPH mitogenic oxidase subunit P65-MOX; AltName: Full=Mitogenic oxidase 1; Short=MOX1 [NCBI NR] gi\|5081798\|gb\|AAD39542.1\|AF152963_1 NADH/NADPH mitogenic oxidase subunit p65-mox [Rattus norvegicus] [NCBI NR] gi\|16758500\|ref\|NP_446135.1\| NADPH oxidase 1 [Rattus norvegicus] [NCBI NR] NADPH oxidase 1 OS=Rattus norvegicus GN=Nox1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None NADPH oxidase homolog 1 [hmr_yeast5_DM3-1_pombe.fasta] NADH/NADPH mitogenic oxidase subunit p65-mox [HMR_022704-rand.fasta] NADPH oxidase 1 [Rattus norvegicus]gi\|5081798\|gb\|AAD39542.1\| NADH/NADPH mitogenic oxidase subunit p65-mox [Rattus norvegicus]gi\|8134593\|sp\|Q9WV87\|NOX1_RAT NADPH oxidase homolog 1 (NOX-1) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic [nrdb_11152004_Chlamydomonas] Tax_Id=10116 NADPH oxidase homolog 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053683) NADH/NADPH mitogenic oxidase subunit p65-mox [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] NADPH oxidase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] NADPH oxidase 1 (NOX-1) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic oxidase 1) (MOX1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] NADH/NADPH mitogenic oxidase subunit p65-mox [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 NADPH OXIDASE HOMOLOG 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] NADPH oxidase homolog 1 (NOX-1) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic oxidase 1) (MOX1) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Nox1 NADPH oxidase 1 [rat-ipi-250309-contam.fasta] NADPH oxidase 1 OS=Rattus norvegicus GN=Nox1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	563 amino acids
Gene Ontology:
Cellular Component:	early endosome [UNKNOWN] endosome [UNKNOWN] NADPH oxidase complex [UNKNOWN][IDA] cytoplasm [UNKNOWN] membrane [IEA] integral to membrane [IEA]
Biological Process:	positive regulation of integrin biosynthetic process [UNKNOWN] proton transport [UNKNOWN] regulation of systemic arterial blood pressure by renin-angiotensin [UNKNOWN] signal transduction [IDA] positive regulation of cell proliferation [UNKNOWN] response to pH [UNKNOWN] electron transport chain [IEA] response to reactive oxygen species [IDA] superoxide anion generation [UNKNOWN][IMP] transport [IEA] response to stress [UNKNOWN] hydrogen peroxide metabolic process [UNKNOWN] positive regulation of smooth muscle cell proliferation [IMP] oxygen and reactive oxygen species metabolic process [UNKNOWN][IMP] superoxide metabolic process [UNKNOWN] intracellular pH elevation [UNKNOWN] angiogenesis [UNKNOWN] extracellular matrix organization [UNKNOWN] oxidation reduction [UNKNOWN] cell migration [UNKNOWN] positive regulation vascular endothelial growth factor production [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN][IPI] iron ion binding [IEA] oxidoreductase activity [IEA] voltage-gated proton channel activity [UNKNOWN] metal ion binding [IEA] FAD binding [IEA] electron carrier activity [IEA] Rac GTPase binding [UNKNOWN] superoxide-generating NADPH oxidase activity [UNKNOWN][IDA][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNWLVNHWL SVLFLVSWLG LNIFLFVYVF LNYEKSDKYY YTREILGTAL ALARASALCL  60
   61 NFNSMVILIP VCRNLLSFLR GTCSFCNHTL RKPLDHNLTF HKLVAYMICI FTAIHIIAHL 120
  121 FNFERYSRSQ QAMDGSLASV LSSLFHPEKE DSWLNPIQSP NVTVMYAAFT SIAGLTGVVA 180
  181 TVALVLMVTS AMEFIRRNYF ELFWYTHHLF IIYIICLGIH GLGGIVRGQT EESMSESHPR 240
  241 NCSYSFHEWD KYERSCRSPH FVGQPPESWK WILAPIAFYI FERILRFYRS RQKVVITKVV 300
  301 MHPCKVLELQ MRKRGFTMGI GQYIFVNCPS ISFLEWHPFT LTSAPEEEFF SIHIRAAGDW 360
  361 TENLIRTFEQ QHSPMPRIEV DGPFGTVSED VFQYEVAVLV GAGIGVTPFA SFLKSIWYKF 420
  421 QRAHNKLKTQ KIYFYWICRE TGAFAWFNNL LNSLEQEMDE LGKPDFLNYR LFLTGWDSNI 480
  481 AGHAALNFDR ATDVLTGLKQ KTSFGRPMWD NEFSRIATAH PKSVVGVFLC GPPTLAKSLR 540
  541 KCCRRYSSLD PRKVQFYFNK ETF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NOX1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: