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Protein Overview: PLCB4_RAT

General Information:
Name(s) found: PLCB4_RAT [Swiss-Prot]
Description(s) found:
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  • gi|12643487|sp|Q9QW07.2|PLCB4_RAT RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; AltName: Full=Phosphoinositide phospholipase C; AltName: Full=Phospholipase C-beta-4; Short=PLC-beta-4 [NCBI NR]
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus GN=Plcb4 PE=1 SV=2 [Swiss-Prot]
  • (Q9QW07) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-beta-4) (Phospholipase C-beta-4) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):3-116759342 Splice isoform A of Q9QW07 [hmr_yeast5_DM3-1_pombe.fasta]
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (Phosphoinositide phospholipase C) (PLC-beta-4) (Phospholipase C-beta-4) [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Splice Isoform A of 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 (Phosphoinositide phospholipase C) (Phospholipase C-beta-4) (PLC-beta-4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SPLICE ISOFORM 1 OF 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA 4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (Phosphoinositide phospholipase C) (Phospholipase C-beta-4) (PLC-beta-4) [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Plcb4 Isoform A of 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 [rat-ipi-250309-contam.fasta]
  • Isoform A of 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus GN=Plcb4 [011711_HMR.fasta]
  • 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus GN=Plcb4 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus GN=Plcb4 PE=2 SV=2 [Aridor_1205.fasta]
    • Organism: Rattus norvegicus
    Length: 1175 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    postsynaptic density [UNKNOWN]
    dendrite [UNKNOWN]
    insoluble fraction [IDA]
    cytoplasm [IDA]
    smooth endoplasmic reticulum [UNKNOWN]
    microsome [UNKNOWN]
    cytosol [UNKNOWN]
    Biological Process: signal transduction [IEA]
    lipid metabolic process [IEA]
    lipid catabolic process [IEA]
    negative regulation of potassium ion transport [IMP]
    phototransduction [NAS]
    Molecular Function: phosphoinositide phospholipase C activity [IEA]
    protein binding [UNKNOWN]
    calcium ion binding [IEA]
    mitogen-activated protein kinase binding [IPI]
    signal transducer activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKPYEFNWQ KEVPSFLQEG AVFDRYEEES FVFEPNCLFK VDEFGFFLTW KSEGKEGQVL  60
   61 ECSLINSIRL AAIPKDPKIL AALESVGKSE NDLEGRILCV CSGTDLVNIG FTYMVAENPE 120
  121 ITKQWVEGLR SIIHNFRANN VSPMTCLKKH WMKLAFLTNT SGKIPVRSIT RTFASGKTEK 180
  181 VIFQALKELG LPSGKNDEIE PAAFTYEKFY ELTQKICPRT DIEDLFKKIN GDKTDYLTVD 240
  241 QLVSFLNEHQ RDPRLNEILF PFYDAKRAMQ IIEMYEPDEE LKKKGLISSD GFCRYLMSDE 300
  301 NAPVFLDRLE LYQEMDHPLA HYFISSSHNT YLTGRQFGGK SSVEMYRQVL LAGCRCVELD 360
  361 CWDGKGEDQE PIITHGKAMC TDILFKDVIQ AIKETAFVTS EYPVILSFEN HCSKYQQYQM 420
  421 SKYCEDLFGD LLLKQALESH PLEPGRLLPS PNDLKRKILI KNKRLKPEVE KKQLEALKSM 480
  481 MEAGESAAPA SILEDDNEEE IESADQEEEA HPEYKFGNEL SADDFSHKEA VANSVKKGLV 540
  541 TVEDEQAWMA SYKYVGATTN IHPYLSTMIN YAQPVKFQGF HVAEERNIHY NMSSFNESVG 600
  601 LGYLKTHAIE FVNYNKRQMS RIYPKGGRVD SSNYMPQIFW NAGCQMVSLN YQTPDLAMQL 660
  661 NQGKFEYNGS CGYLLKPDFM RRPDRTFDPF SETPVDGVIA ATCSVQVISG QFLSDKKIGT 720
  721 YVEVDMYGLP TDTIRKEFRT RMVMNNGLNP VYNEESFVFR KVILPDLAVL RIAVYDDNNK 780
  781 LIGQRILPLD GLQAGYRHIS LRNEGNKPLS LPTIFCNIVL KTYVPDGFGD IVDALSDPKK 840
  841 FLSITEKRAD QLRAMGIETS DIADVPSDTS KNDKKGKANP AKANVTPQSS SELRPTTTAA 900
  901 LGSGQEAKKG IELIPQVRIE DLKQMKAYLK HLKKQQKELN SLKKKHAKEH STMQKLHCTQ 960
  961 VDKIVAQYDK EKSTHEKILE KAMKKKGGSN CLEIKKETEI KIQTLTSDHK SKVKEIVAQH1020
 1021 TKEWSEMINT HSAEEQEIRD LHLSQQCELL RKLLINAHEQ QTQQLKLSHD RESKEMRAHQ1080
 1081 AKISMENSKA ISQDKSIKNK AERERRVREL NSSNTKKFLE ERKRLAMKQS KEMDQLKKVQ1140
 1141 LEHLEFLEKQ NEQAKEMQQM VKLEAEMDRR PATVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle