General Information: |
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Name(s) found: |
PPARA_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 468 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[IDA]
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Biological Process: |
negative regulation of sequestering of triglyceride
[UNKNOWN][IEA]
negative regulation of appetite [ISS] epidermis development [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IDA] negative regulation of blood pressure [IMP] positive regulation of transcription [UNKNOWN][IEA] lipoprotein metabolic process [IMP] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] fatty acid metabolic process [UNKNOWN][IMP] heart development [IEP] wound healing [UNKNOWN][IEA] response to hypoxia [IDA] response to insulin stimulus [IMP] positive regulation of fatty acid oxidation [IEA] negative regulation of macrophage derived foam cell differentiation [UNKNOWN][IEA] negative regulation of cholesterol storage [UNKNOWN][IEA] negative regulation of receptor biosynthetic process [UNKNOWN][IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] regulation of fatty acid metabolic process [UNKNOWN][TAS] |
Molecular Function: |
zinc ion binding
[IEA]
protein domain specific binding [IDA] drug binding [UNKNOWN][ISS] lipid binding [UNKNOWN][ISS] sequence-specific DNA binding [IEA] receptor activity [UNKNOWN] DNA binding [UNKNOWN] transcription factor activity [IEA] protein binding [UNKNOWN][IPI] ligand-dependent nuclear receptor activity [UNKNOWN][IMP] metal ion binding [IEA] ligand-regulated transcription factor activity [IDA] steroid hormone receptor activity [TAS] MDM2 binding [IPI] transcription activator activity [UNKNOWN][IMP][ISS] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MVDTESPICP LSPLEADDLE SPLSEEFLQE MGNIQEISQS LGEESSGSFS FADYQYLGSC 60 61 PGSEGSVITD TLSPASSPSS VSCPAVPTST DESPGNALNI ECRICGDKAS GYHYGVHACE 120 121 GCKGFFRRTI RLKLAYDKCD RSCKIQKKNR NKCQYCRFHK CLSVGMSHNA IRFGRMPRSE 180 181 KAKLKAEILT CEHDLKDSET ADLKSLAKRI HEAYLKNFNM NKVKARVILA GKTSNNPPFV 240 241 IHDMETLCMA EKTLVAKMVA NGVENKEAEV RFFHCCQCMS VETVTELTEF AKAIPGFANL 300 301 DLNDQVTLLK YGVYEAIFTM LSSLMNKDGM LIAYGNGFIT REFLKNLRKP FCDIMEPKFD 360 361 FAMKFNALEL DDSDISLFVA AIICCGDRPG LLNIGYIEKL QEGIVHVLKL HLQSNHPDDT 420 421 FLFPKLLQKM VDLRQLVTEH AQLVQVIKKT ESDAALHPLL QEIYRDMY |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)