Protein Overview: PPARA_RAT

General Information:
Name(s) found:	PPARA_RAT [Swiss-Prot]
Description(s) found: Found 20 descriptions. SHOW ALL	Peroxisome proliferator-activated receptor alpha OS=Rattus norvegicus GN=Ppara PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	468 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	negative regulation of sequestering of triglyceride [UNKNOWN][IEA] negative regulation of appetite [ISS] epidermis development [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IDA] negative regulation of blood pressure [IMP] positive regulation of transcription [UNKNOWN][IEA] lipoprotein metabolic process [IMP] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] fatty acid metabolic process [UNKNOWN][IMP] heart development [IEP] wound healing [UNKNOWN][IEA] response to hypoxia [IDA] response to insulin stimulus [IMP] positive regulation of fatty acid oxidation [IEA] negative regulation of macrophage derived foam cell differentiation [UNKNOWN][IEA] negative regulation of cholesterol storage [UNKNOWN][IEA] negative regulation of receptor biosynthetic process [UNKNOWN][IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] regulation of fatty acid metabolic process [UNKNOWN][TAS]
Molecular Function:	zinc ion binding [IEA] protein domain specific binding [IDA] drug binding [UNKNOWN][ISS] lipid binding [UNKNOWN][ISS] sequence-specific DNA binding [IEA] receptor activity [UNKNOWN] DNA binding [UNKNOWN] transcription factor activity [IEA] protein binding [UNKNOWN][IPI] ligand-dependent nuclear receptor activity [UNKNOWN][IMP] metal ion binding [IEA] ligand-regulated transcription factor activity [IDA] steroid hormone receptor activity [TAS] MDM2 binding [IPI] transcription activator activity [UNKNOWN][IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDTESPICP LSPLEADDLE SPLSEEFLQE MGNIQEISQS LGEESSGSFS FADYQYLGSC  60
   61 PGSEGSVITD TLSPASSPSS VSCPAVPTST DESPGNALNI ECRICGDKAS GYHYGVHACE 120
  121 GCKGFFRRTI RLKLAYDKCD RSCKIQKKNR NKCQYCRFHK CLSVGMSHNA IRFGRMPRSE 180
  181 KAKLKAEILT CEHDLKDSET ADLKSLAKRI HEAYLKNFNM NKVKARVILA GKTSNNPPFV 240
  241 IHDMETLCMA EKTLVAKMVA NGVENKEAEV RFFHCCQCMS VETVTELTEF AKAIPGFANL 300
  301 DLNDQVTLLK YGVYEAIFTM LSSLMNKDGM LIAYGNGFIT REFLKNLRKP FCDIMEPKFD 360
  361 FAMKFNALEL DDSDISLFVA AIICCGDRPG LLNIGYIEKL QEGIVHVLKL HLQSNHPDDT 420
  421 FLFPKLLQKM VDLRQLVTEH AQLVQVIKKT ESDAALHPLL QEIYRDMY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PPARA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: