Protein Overview: AKC1H_RAT

General Information:
Name(s) found:	AKC1H_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|72679367\|gb\|AAI00249.1\| Aldo-keto reductase family 1, member C18 [Rattus norvegicus] [NCBI NR] gi\|506415\|gb\|AAA40601.1\| 20-alpha-hydroxysteroid dehydrogenase [NCBI NR] gi\|471152\|dbj\|BAA03317.1\| 20-alpha-hydroxysteroid dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|19924035\|ref\|NP_612519.1\| aldo-keto reductase family 1, member C18 [Rattus norvegicus] [NCBI NR] gi\|1709623\|sp\|P51652.1\|AKC1H_RAT RecName: Full=Aldo-keto reductase family 1 member C18; AltName: Full=20-alpha-hydroxysteroid dehydrogenase; Short=20-alpha-HSD; AltName: Full=HSD1 [NCBI NR] gi\|149020966\|gb\|EDL78573.1\| aldo-keto reductase family 1, member C18, isoform CRA_a [Rattus norvegicus] [NCBI NR] (P51652) 20-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) (20-alpha-HSD) (HSD1) [Swiss-Prot] Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):17-77274715;17-77274715 20-alpha-hydroxysteroid dehydrogenase [hmr_yeast5_DM3-1_pombe.fasta] 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-hydroxysteroid dehydrogenase [HMR_022704-rand.fasta] 20 alpha-hydroxysteroid dehydrogenase [Rattus norvegicus]gi\|471152\|dbj\|BAA03317.1\| 20-alpha-hydroxysteroid dehydrogenase [Rattus norvegicus]gi\|1709623\|sp\|P51652\|PE2R_RAT 20-alpha-hydroxysteroid dehydrogenase (20-alpha-HSD) (HSD1)gi\|506415\|gb\|AAA40601.1 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Aldo-keto reductase family 1 member C18 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_138510) 20 alpha-hydroxysteroid dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 20-alpha-hydroxysteroid dehydrogenase [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Aldo-keto reductase family 1 member C18 (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (HSD1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 20-alpha-hydroxysteroid dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aldo-keto reductase family 1, member C18 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aldo-keto reductase family 1, member C18, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Aldo-keto reductase family 1, member C18 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 20-alpha-hydroxysteroid dehydrogenase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] 20 alpha-hydroxysteroid dehydrogenase [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Akr1c18 Aldo-keto reductase family 1 member C18 [rat-ipi-250309-contam.fasta] Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	323 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] cytoplasm [IEA] cytosol [IDA] intracellular [UNKNOWN]
Biological Process:	progesterone metabolic process [IDA] progesterone catabolic process [UNKNOWN][IEA] oxidation reduction [IEA] regulation of steroid biosynthetic process [IDA] parturition [UNKNOWN][IEA]
Molecular Function:	oxidoreductase activity [IEA] 20-alpha-hydroxysteroid dehydrogenase activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSKIQKMEL NDGHSIPVLG FGTYATEENL RKKSMESTKI AIDVGFRHID CSHLYQNEEE  60
   61 IGQAIVSKIE DGTVKREDIF YTSKLWSTSH RPELVRPSLE NSLRKLNLDY VDLYLIHFPV 120
  121 SLKPGDELLP QDEHGNLILD TVDLCDTWEA MEKCKDAGLA KSIGVSNFNR RQLEKILNKP 180
  181 GLKHRPVCNQ VECHLYLNQS KLLAYCKMND IVLVAYGALG TQRYKYCINE DTPVLLDDPI 240
  241 LCTMAKKYKR TPALIALRYQ LERGIVTLVK SFNEERIREN LQVFDFQLAS DDMEILDNLD 300
  301 RNLRYFPANM FKAHPNFPFS DEY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: AKC1H_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: