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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: 20-alpha-hydroxysteroid dehydrogenase activity
Acc: GO:0047006
Aspect: Molecular Function
Desc: Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.
Synonyms:
  • 20alpha-HSD
  • 20alpha-HSDH
  • 20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity
  • 20alpha-hydroxysteroid dehydrogenase
  • 20alpha-hydroxy steroid dehydrogenase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047006 - 20-alpha-hydroxysteroid dehydrogenase activity (interactive image map)

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